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A0A8K1HNM6 · A0A8K1HNM6_9NEOP

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

137650100150200250300350
TypeIDPosition(s)Description
Binding site84Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site98Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site183Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site197Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site202a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      cob

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • B3_45
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Polyneoptera > Dictyoptera > Blattodea > Blaberoidea > Blaberidae > Geoscapheinae > Geoscapheus

Accessions

  • Primary accession
    A0A8K1HNM6

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane31-57Helical
Transmembrane78-99Helical
Transmembrane111-134Helical
Transmembrane141-159Helical
Transmembrane179-201Helical
Transmembrane231-251Helical
Transmembrane263-282Helical
Transmembrane289-307Helical
Transmembrane319-339Helical
Transmembrane346-363Helical

Keywords

Interaction

Subunit

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-210Cytochrome b/b6 N-terminal region profile
Domain211-376Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    376
  • Mass (Da)
    43,370
  • Last updated
    2022-08-03 v1
  • MD5 Checksum
    E41F9D16D119F62F9AC35C0627454A3E
MNKSIRTTHPLLKIFNNALIDLPTPSNINSWWNFGSLLGLCLVIQIITGIFLGMHYCSNIEMAFYSVNHICRDVNYGWLLRTLHDNGASVFFVCIYMHVGRWMYYGSYKFIQTWSIGVMILFLTMAAAFMGYVLPWGQMSFWGATMITNLLSAVPYMGVDLVQWVWGGFAVDNATLNRFFTFHFLLSFIIAAMVMIHLLFLHQTGSNNPTGLNSNLDKIPFHPYFSIKDTFGFIMVIMLLTTLTLMDPYILGDPDNFIPANPLVTPIHIQPEWYFLFAYAILRSIPNKLGVIALVMSIAIFFFMPLYKSNFRGIQFYPINQIMFWIMANTVILLTWIGARPVEDPYIITGQILTIIYFMFYMTSPMVTKFWDIIIK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MW996580
EMBL· GenBank· DDBJ
UBN08725.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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