A0A8K0P7H3 · A0A8K0P7H3_LADFU

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site56-60NAD+ (UniProtKB | ChEBI)
Binding site66-68NAD+ (UniProtKB | ChEBI)
Binding site139-142NAD+ (UniProtKB | ChEBI)
Active site159Proton acceptor
Binding site167Zn2+ (UniProtKB | ChEBI)
Binding site170Zn2+ (UniProtKB | ChEBI)
Binding site191Zn2+ (UniProtKB | ChEBI)
Binding site193Zn2+ (UniProtKB | ChEBI)
Binding site230-231NAD+ (UniProtKB | ChEBI)
Binding site254-256NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionNAD+ binding
Molecular FunctionNAD-dependent histone deacetylase activity
Molecular Functiontransferase activity
Molecular Functionzinc ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD-dependent protein deacetylase
  • EC number

Gene names

    • ORF names
      J437_LFUL015326

Organism names

Accessions

  • Primary accession
    A0A8K0P7H3

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-15
ChainPRO_503546467816-303NAD-dependent protein deacetylase

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain29-288Deacetylase sirtuin-type

Sequence similarities

Belongs to the sirtuin family. Class I subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    303
  • Mass (Da)
    34,046
  • Last updated
    2022-08-03 v1
  • Checksum
    4F6467151A3D97D5
MVLTALRLITGFIDACSVLKCRPPNIRNYSTSSETIKAVSSYIRDKCESIVVMAGAGLSTPSGIPDFRSPGTGLYHNLQKYNLPYPEAIFDIQYFVNNPMPFITLAQELYPGQKYRPNLAHYFVRLLHEKGKLLRMYTQNIDGLERLSGIPGDKLIEAHGTFHSASCIVCGDEHDPEIVKQTILSGKVHLCHCKGYVKPDIVFFGEQLPAKFWLHNLDTADTDLLIVLGTSLEVQPFASICDAVPRNTPRLLINRELVGSFGYRDFDNMLVGDIIESIRNLAKDIGWEEELSKLYETCEKRST

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KZ308858
EMBL· GenBank· DDBJ
KAG8234918.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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