A0A8K0JWJ8 · A0A8K0JWJ8_LADFU
- ProteinNeural-cadherin
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1676 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Cadherins are calcium-dependent cell adhesion proteins.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | adherens junction | |
Cellular Component | catenin complex | |
Molecular Function | cadherin binding | |
Molecular Function | calcium ion binding | |
Biological Process | adherens junction organization | |
Biological Process | animal organ development | |
Biological Process | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules | |
Biological Process | cell differentiation | |
Biological Process | cell morphogenesis | |
Biological Process | cell-cell adhesion mediated by cadherin | |
Biological Process | cell-cell junction assembly | |
Biological Process | developmental growth | |
Biological Process | establishment of planar polarity | |
Biological Process | establishment or maintenance of cell polarity | |
Biological Process | homophilic cell adhesion via plasma membrane adhesion molecules |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameNeural-cadherin
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Palaeoptera > Odonata > Epiprocta > Anisoptera > Libellulidae > Ladona
Accessions
- Primary accessionA0A8K0JWJ8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type I membrane protein
Membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1474-1495 | Helical | ||||
Sequence: FIIAIVACLFALLILVLVFVVY |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 791↔800 | |||||
Sequence: CPNGYGGPRC | ||||||
Disulfide bond | 1063↔1072 | |||||
Sequence: CQPGWTGPHC | ||||||
Disulfide bond | 1319↔1336 | |||||
Sequence: CLNGGVCVNQEPSLRYRC | ||||||
Disulfide bond | 1338↔1347 | |||||
Sequence: CPEGFWGENC | ||||||
Disulfide bond | 1430↔1447 | |||||
Sequence: CLNGGECIDYDDARRFAC | ||||||
Disulfide bond | 1449↔1458 | |||||
Sequence: CKGSYTGRHC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 7-53 | Cadherin | ||||
Sequence: PLDRDQPSGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDINDNAPIF | ||||||
Domain | 54-165 | Cadherin | ||||
Sequence: PHGVYLGNVTENGTAGMLVMTMTAVDYDDPSEGTNARLTYSIEKNVIEEETGSPIFEIEPETGVIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIRVKDINDMPPQF | ||||||
Domain | 166-284 | Cadherin | ||||
Sequence: TKDEWFTEVDETDGSNLPEMPILTVTVHDEDETNKFQYKVIENSGYGADKFTMVRNNDGTGSLKIVQPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPQF | ||||||
Domain | 285-389 | Cadherin | ||||
Sequence: ERPNIEVSVYENAEVGKSLETFKATDPDQGGRSRVSYAIDRTSDRRRQFAISKEGTVSIQRSLDREDTPRHQVKILAIDDGVPPKTATATLTVVVQDINDNAPTF | ||||||
Domain | 389-508 | Cadherin | ||||
Sequence: FLRDYRPVLPEHVPPRKVVEVLATDDDDRSKSNGPPFTFRMDPNAHDVIRASFKVEHDQKGANGDGMAVVSSLRSFDREQQKEYLIPIVIKDSGNPAMSGTSTLTVVIGDVNDNKMQPGS | ||||||
Domain | 765-801 | EGF-like | ||||
Sequence: RGESCRSTPCHNGGRCMEGRYGLTCVCPNGYGGPRCQ | ||||||
Domain | 802-1009 | Laminin G | ||||
Sequence: QTTRHFRGSGWAWYPPLEMCENSHLSLEFITRKADGTLLYNGPIVAPEPEEVMVSDFISVELERGQPRVLVDFGSGTLELRVRTKKALDDGEWHRLDIFWDTENVRVVVDYCKSADVTELEDGSPPEFEGNSCQAEGTVPPFAEYLNVNAPLQLGGLYVESGLDPAHFRWQSMPLGKPFDGCIRNVVHNSKLYDLAHPGLSRHSVAGC | ||||||
Region | 1021-1041 | Disordered | ||||
Sequence: GGGDGGGSSTGVSGHSVGSGG | ||||||
Domain | 1037-1073 | EGF-like | ||||
Sequence: VGSGGAGLRCWERGTCVGSFGEGRCECQPGWTGPHCS | ||||||
Domain | 1076-1267 | Laminin G | ||||
Sequence: TIPTTFRPQSYVKYALSFEPDRFSTSIQLRFRTREEHGELFRVSDQHNREYGILEIRDSRLHFRYNLNSLRTEEKDLWLSAVTVDDGQWHTAKVSRYGSAAILELDGGEGRRYNETFKFEGHQWLLVDKQEGVYAGGKAEYTGVRTFEVYADYQKGCLDDIRLEGKLLPLPPAINGTQWGQATMARNLDRHC | ||||||
Domain | 1310-1348 | EGF-like | ||||
Sequence: DRDECIDAPCLNGGVCVNQEPSLRYRCICPEGFWGENCE | ||||||
Domain | 1420-1459 | EGF-like | ||||
Sequence: NEEECKWWRPCLNGGECIDYDDARRFACRCKGSYTGRHCE | ||||||
Region | 1603-1676 | Disordered | ||||
Sequence: KRADSDPNAPPFDDLRNYAYEGGGSTAGSLSSLASDDNEQDFDYLNGWGPRFSKLADMYGQGESEEEEEEEEEQ | ||||||
Compositional bias | 1626-1641 | Polar residues | ||||
Sequence: GSTAGSLSSLASDDNE |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,676
- Mass (Da)186,040
- Last updated2022-08-03 v1
- Checksum1DF61B8808A488E5
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1626-1641 | Polar residues | ||||
Sequence: GSTAGSLSSLASDDNE |
Keywords
- Technical term