A0A8J9VYF9 · A0A8J9VYF9_BRALA
- ProteinATP-binding cassette sub-family B member 6
- GeneABCB6
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids839 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.heme b (in)CHEBI:60344
+ CHEBI:30616 + CHEBI:15377 = heme b (out)CHEBI:60344+ CHEBI:456216 + CHEBI:43474 + CHEBI:15378 - pheophorbide a(in) + ATP + H2O = pheophorbide a(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- protoporphyrin IX(in) + ATP + H2O = protoporphyrin IX(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | early endosome membrane | |
Cellular Component | extracellular region | |
Cellular Component | Golgi membrane | |
Cellular Component | lysosomal membrane | |
Cellular Component | melanosome membrane | |
Cellular Component | mitochondrial outer membrane | |
Cellular Component | multivesicular body membrane | |
Molecular Function | ABC-type heme transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | heme binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-binding cassette sub-family B member 6
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Cephalochordata > Leptocardii > Amphioxiformes > Branchiostomatidae > Branchiostoma
Accessions
- Primary accessionA0A8J9VYF9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Endosome membrane ; Multi-pass membrane protein
Golgi apparatus membrane ; Multi-pass membrane protein
Mitochondrion outer membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 29-50 | Helical | |||
Transmembrane | 71-90 | Helical | |||
Transmembrane | 96-117 | Helical | |||
Transmembrane | 137-157 | Helical | |||
Transmembrane | 177-194 | Helical | |||
Transmembrane | 255-278 | Helical | |||
Transmembrane | 298-326 | Helical | |||
Transmembrane | 372-394 | Helical | |||
Transmembrane | 400-421 | Helical | |||
Transmembrane | 522-540 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 258-545 | ABC transmembrane type-1 | |||
Domain | 579-813 | ABC transporter | |||
Region | 817-839 | Disordered | |||
Compositional bias | 823-839 | Basic and acidic residues | |||
Sequence similarities
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length839
- Mass (Da)95,556
- Last updated2022-08-03 v1
- Checksum9C43414BF5D32FC1
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 823-839 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
OV696695 EMBL· GenBank· DDBJ | CAH1238959.1 EMBL· GenBank· DDBJ | Genomic DNA |