A0A8J5IL42 · A0A8J5IL42_9STRA
- Protein2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids554 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
Catalytic activity
- a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+
a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol RHEA-COMP:10858 + CHEBI:59789 = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol RHEA-COMP:10859 + CHEBI:57856 + CHEBI:15378
Pathway
Cofactor biosynthesis; ubiquinone biosynthesis.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extrinsic component of mitochondrial inner membrane | |
Molecular Function | 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity | |
Molecular Function | peroxidase activity | |
Biological Process | methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Sar > Stramenopiles > Oomycota > Peronosporales > Peronosporaceae > Phytophthora
Accessions
- Primary accessionA0A8J5IL42
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
Interaction
Subunit
Component of a multi-subunit COQ enzyme complex.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 32-234 | Heme haloperoxidase family profile | ||||
Sequence: DVSGFPPPNSAPNHRSPCPALNSLANHGYLPRDGKALTPQMIREAVMDVYNVDESLAERLTRPLPAELTLADLSIHGFIEHDASLVHDDTYLERDPAQINTTLAGNLFAKSMDGKLNKHSMATARRERETQCKKENPEYAFPVKAQATAYGESALLLIAMGDYESKTVSVDHAKSFLVEEKIPDDFQRSDKPISTAAAFYLAA |
Sequence similarities
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length554
- Mass (Da)61,390
- Last updated2022-05-25 v1
- Checksum4CFC14925AA9927A
Keywords
- Technical term