A0A8J4T8F3 · A0A8J4T8F3_9BACT

  • Protein
    6,7-dimethyl-8-ribityllumazine synthase
  • Gene
    ribH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site345-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site67-695-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site91-935-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site96-97(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)
Active site99Proton donor
Binding site1245-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site138(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentriboflavin synthase complex
Molecular Function6,7-dimethyl-8-ribityllumazine synthase activity
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6,7-dimethyl-8-ribityllumazine synthase
  • EC number
  • Short names
    DMRL synthase
    ; LS
    ; Lumazine synthase

Gene names

    • Name
      ribH
    • ORF names
      Udaeo2_26020

Organism names

  • Taxonomic identifier
  • Strain
    • AEW3
  • Taxonomic lineage
    Bacteria > Verrucomicrobiota > Spartobacteria > Chthoniobacterales > Chthoniobacteraceae > Candidatus Udaeobacter

Accessions

  • Primary accession
    A0A8J4T8F3

Proteomes

Subcellular Location

Family & Domains

Sequence similarities

Belongs to the DMRL synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    166
  • Mass (Da)
    18,267
  • Last updated
    2022-05-25 v1
  • Checksum
    FDAA4CE12EEF9562
MRIEDCGLNECRPTRRGPRVEKGKRTFQIVASRFNAPYVQGLVDHVTGELHELVPGAAISIHRVPGSFEIPVVVRELARKKKADAIIACGVVMRGETNHAKNLSRSVTDALQRIAVDYGVPVINVVLSFDNEKQARQRCLENTINRGTEAARAAVEIAGAMSKLRK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAALOD010000079
EMBL· GenBank· DDBJ
KAF5407285.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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