A0A8J2Z7B0 · A0A8J2Z7B0_9PROT
- ProteinUDP-N-acetylmuramate--L-alanine ligase
- GenemurC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids484 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation.
Catalytic activity
- UDP-N-acetyl-alpha-D-muramate + L-alanine + ATP = UDP-N-acetyl-alpha-D-muramoyl-L-alanine + ADP + phosphate + H+
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UDP-N-acetylmuramate-L-alanine ligase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylmuramate--L-alanine ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Acetobacteraceae > Caldovatus
Accessions
- Primary accessionA0A8J2Z7B0
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 11-108 | Mur ligase N-terminal catalytic | ||||
Sequence: IHFVGIGGIGMSGIAEVLHNLGYRVQGSDIAENYNVARLREAGVPVAIGHDAANLGAAQVVVVSSAVRRDNPEVAAARARLIPVVRRAEMLAELMRLK | ||||||
Domain | 113-298 | Mur ligase central | ||||
Sequence: IGGTHGKTTTTSLVAAVLEAARLDPTVINGGIVNAYGTNTRLGAGEWMVVEADESDGSFLRLPAVVAVVTNMDPEHLDHWGTAEAMKEGYAQFVGNIPFYGFAVLCMDHPEVQAMIPRLSDRRIVTYGFSPQADVRAERLITDRMGATFEVTVTDRALGRSRTLKPFRLPMLGSHNVQNALAAIAV | ||||||
Domain | 321-451 | Mur ligase C-terminal | ||||
Sequence: RRFTRVGEAGGVTVIDDYGHHPVEIAAVLKAARQAGARDVIAVVQPHRYSRLHSLFEEFCQCMNDAGTVIVADVYPAGEPPIPGVDKDALVEGLRAHGHRSVVPLPGPESLAEMINAIARPGDYVVCLGAG |
Sequence similarities
Belongs to the MurCDEF family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length484
- Mass (Da)51,592
- Last updated2022-05-25 v1
- Checksum0830AE78E812DBD7
Keywords
- Technical term