A0A8J2S6W9 · A0A8J2S6W9_9CRUS
- ProteinG-protein coupled receptor
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1668 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | calcium ion binding | |
Molecular Function | G protein-coupled receptor activity | |
Biological Process | cell surface receptor signaling pathway | |
Biological Process | establishment of planar polarity | |
Biological Process | establishment or maintenance of cell polarity | |
Biological Process | homophilic cell adhesion via plasma membrane adhesion molecules |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Recommended nameG-protein coupled receptor
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Crustacea > Branchiopoda > Diplostraca > Cladocera > Anomopoda > Daphniidae > Daphnia
Accessions
- Primary accessionA0A8J2S6W9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1055-1078 | Helical | ||||
Sequence: LISYVGSGLSILGLSITVLLYSLF | ||||||
Transmembrane | 1090-1114 | Helical | ||||
Sequence: LLNLSISLLMLNVIFLVGSILGTAY | ||||||
Transmembrane | 1161-1180 | Helical | ||||
Sequence: LSWMLVEAVHMYQLLILVFA | ||||||
Transmembrane | 1192-1213 | Helical | ||||
Sequence: VAAWGVPLIVVVTTAVLCLDYY | ||||||
Transmembrane | 1233-1259 | Helical | ||||
Sequence: YSAFIGPTCLILLINSTVFFMVLRVIL | ||||||
Transmembrane | 1293-1312 | Helical | ||||
Sequence: GAVTVMALLGVTWVAGAVAI | ||||||
Transmembrane | 1318-1340 | Helical | ||||
Sequence: VMTYVFCVCNSLQGFVIFIVRVV |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-27 | |||||
Sequence: MGISMAPLGQRLVLLVFSVVMTTQVFG | ||||||
Chain | PRO_5035272357 | 28-1668 | G-protein coupled receptor | |||
Sequence: LQFDKSRVLEISAGAPPGTIVGKLRVISRAAGGVLTGDNVGVNFSLHNSSDYADFHVEPKTGLLSVTKRVDRPVNSTYQIIVRAMLAKSRSGDTDRFEIRVTAPPQATDGSLLLLDSNQYEGEIEPDSPIGMAIIEVMAFVNGSHNQMPGNVTYFMEPFPDEKNISFTAIKDWFRMDNRTGVVQLLQSPQPGIKAHNVSFMIGAMERDKSLNAKAPAVVLIHGLPRPRNVTVTKLSADTAVICWKFPLAAGAQGYVLRYWRHPASITQSLTSSAENEQISDSKPIPLELKIIDLDSRNGTVANTTKDEIRTVCSSLKQLESEAAYKLQVLACGGDAECGDSLGPASAVLHFTTQTNHCSLEGTCVTGECQISFEAPGFECLCHSGNYGPRCELYNPCVLTPCQNGATCRNFTDSTYECQCPEGFDGENCVVPIGPPCLHEEPCLNNGTCAKEGCDCLPGYEGFQCENFNPCWNDPCPKEANCTVLLDSDEFQCVCPLGFRGRDCEEAIDYCTLDPCQNDGQCSSQNGAYHCECTSGFYGVACEQDVDECQSNPCKNNSTCHNLPGSFTCVCPPGFTGMRCEDKVEACLSFPCQNKAVCQNDFENMSYMCFCRPGYDGRDCENNIDDCNPDPCMNGATCRDLTDAFECLCKTGFSGFTCDYEEPCPEDVEESVEKGFFHWPVTEPGQTVTVACPYGTLTTLEGMSKRPADISNGLVTDTEFRERQERTKFNGTTTTVAATAVRSCERFPNGTIGWNLSDLSACREQRLAIAEERSAILENNSVAGKNLTLIGVEQVADEVVNLVDDALMDLKVAHNFFNTLSNVMEVDDEVLGASNNSCDRLLDAIERYTSQVALEPDKPVTLATPNIAIETLLHSKPESYSFRPSFEGDPSVNSLISLTIPKQALEGSRDGVRLQFVSYRSGKLFQSRTNRLPGQPAMVIAATVGHVSVSGLSEPVTYTMPLVNSSSFYSCVYWDELEKEWSTKGVKTTKTESGMIECLSDHLTAFSILLDPTPMDRISGYHEYILRLISYVGSGLSILGLSITVLLYSLFRNLRRDRGGKILLNLSISLLMLNVIFLVGSILGTAYKNVDMEQRAQMSERIWAAGTESPVSQAHVDICTALTISVHYLVLSSLSWMLVEAVHMYQLLILVFANSETCFMLKRTVAAWGVPLIVVVTTAVLCLDYYQDPTGQTCGRMSHAHLTVYYSAFIGPTCLILLINSTVFFMVLRVILLQGQRGRAVGKVATENGNGAGGANRLMIMAQLRGAVTVMALLGVTWVAGAVAIGPVKVVMTYVFCVCNSLQGFVIFIVRVVQYPEARQSFVTLWNTGQTHIPYDATRHSSGPTQFNSSGSATGQSSAHAVLRARKTLSINSSRSPGSSGRNMLSITRGPDDSLTPSQAPTLALGGTTDSNSPSPSYQHWFPSATASPASNGSTQSRFRRIFGNLGLEPSSLRLSSKSNGKSNGSHSLLERHVSGATNPPPSPGDKSHQILGEPSPLPEELIKPNFIIGEEISLLHPGAAASSAEPSAGTNKRSSVISAGGSISKEGANTSWTYLRPEDEIGDNDQLPTDGFIARRRAVSFVVNLPSDGSNSSSTNDDRRVPPVRRTQSLCEDPPELSVIFRNGPQQQSSLPRQDPLFHS | ||||||
Disulfide bond | 409↔418 | |||||
Sequence: CHSGNYGPRC | ||||||
Disulfide bond | 447↔456 | |||||
Sequence: CPEGFDGENC | ||||||
Disulfide bond | 483↔492 | |||||
Sequence: CLPGYEGFQC | ||||||
Disulfide bond | 503↔520 | |||||
Sequence: CPKEANCTVLLDSDEFQC | ||||||
Disulfide bond | 522↔531 | |||||
Sequence: CPLGFRGRDC | ||||||
Disulfide bond | 560↔569 | |||||
Sequence: CTSGFYGVAC | ||||||
Disulfide bond | 598↔607 | |||||
Sequence: CPPGFTGMRC | ||||||
Disulfide bond | 619↔636 | |||||
Sequence: CQNKAVCQNDFENMSYMC | ||||||
Disulfide bond | 638↔647 | |||||
Sequence: CRPGYDGRDC | ||||||
Disulfide bond | 676↔685 | |||||
Sequence: CKTGFSGFTC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 30-155 | Cadherin | ||||
Sequence: FDKSRVLEISAGAPPGTIVGKLRVISRAAGGVLTGDNVGVNFSLHNSSDYADFHVEPKTGLLSVTKRVDRPVNSTYQIIVRAMLAKSRSGDTDRFEIRVTAPPQATDGSLLLLDSNQYEGEIEPDS | ||||||
Domain | 381-419 | EGF-like | ||||
Sequence: QTNHCSLEGTCVTGECQISFEAPGFECLCHSGNYGPRCE | ||||||
Domain | 420-457 | EGF-like | ||||
Sequence: LYNPCVLTPCQNGATCRNFTDSTYECQCPEGFDGENCV | ||||||
Domain | 460-493 | EGF-like | ||||
Sequence: IGPPCLHEEPCLNNGTCAKEGCDCLPGYEGFQCE | ||||||
Domain | 494-532 | EGF-like | ||||
Sequence: NFNPCWNDPCPKEANCTVLLDSDEFQCVCPLGFRGRDCE | ||||||
Domain | 534-570 | EGF-like | ||||
Sequence: AIDYCTLDPCQNDGQCSSQNGAYHCECTSGFYGVACE | ||||||
Domain | 572-608 | EGF-like | ||||
Sequence: DVDECQSNPCKNNSTCHNLPGSFTCVCPPGFTGMRCE | ||||||
Domain | 610-648 | EGF-like | ||||
Sequence: KVEACLSFPCQNKAVCQNDFENMSYMCFCRPGYDGRDCE | ||||||
Domain | 650-686 | EGF-like | ||||
Sequence: NIDDCNPDPCMNGATCRDLTDAFECLCKTGFSGFTCD | ||||||
Domain | 664-793 | G-protein coupled receptors family 2 profile 1 | ||||
Sequence: TCRDLTDAFECLCKTGFSGFTCDYEEPCPEDVEESVEKGFFHWPVTEPGQTVTVACPYGTLTTLEGMSKRPADISNGLVTDTEFRERQERTKFNGTTTTVAATAVRSCERFPNGTIGWNLSDLSACREQR | ||||||
Domain | 1053-1342 | G-protein coupled receptors family 2 profile 2 | ||||
Sequence: LRLISYVGSGLSILGLSITVLLYSLFRNLRRDRGGKILLNLSISLLMLNVIFLVGSILGTAYKNVDMEQRAQMSERIWAAGTESPVSQAHVDICTALTISVHYLVLSSLSWMLVEAVHMYQLLILVFANSETCFMLKRTVAAWGVPLIVVVTTAVLCLDYYQDPTGQTCGRMSHAHLTVYYSAFIGPTCLILLINSTVFFMVLRVILLQGQRGRAVGKVATENGNGAGGANRLMIMAQLRGAVTVMALLGVTWVAGAVAIGPVKVVMTYVFCVCNSLQGFVIFIVRVVQY | ||||||
Region | 1363-1382 | Disordered | ||||
Sequence: DATRHSSGPTQFNSSGSATG | ||||||
Region | 1397-1462 | Disordered | ||||
Sequence: SINSSRSPGSSGRNMLSITRGPDDSLTPSQAPTLALGGTTDSNSPSPSYQHWFPSATASPASNGST | ||||||
Compositional bias | 1477-1500 | Polar residues | ||||
Sequence: PSSLRLSSKSNGKSNGSHSLLERH | ||||||
Region | 1477-1526 | Disordered | ||||
Sequence: PSSLRLSSKSNGKSNGSHSLLERHVSGATNPPPSPGDKSHQILGEPSPLP | ||||||
Region | 1549-1571 | Disordered | ||||
Sequence: ASSAEPSAGTNKRSSVISAGGSI | ||||||
Compositional bias | 1552-1571 | Polar residues | ||||
Sequence: AEPSAGTNKRSSVISAGGSI | ||||||
Compositional bias | 1612-1626 | Polar residues | ||||
Sequence: NLPSDGSNSSSTNDD | ||||||
Region | 1612-1668 | Disordered | ||||
Sequence: NLPSDGSNSSSTNDDRRVPPVRRTQSLCEDPPELSVIFRNGPQQQSSLPRQDPLFHS | ||||||
Compositional bias | 1649-1668 | Polar residues | ||||
Sequence: FRNGPQQQSSLPRQDPLFHS |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,668
- Mass (Da)181,065
- Last updated2022-05-25 v1
- Checksum9029D4149E3C6011
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1477-1500 | Polar residues | ||||
Sequence: PSSLRLSSKSNGKSNGSHSLLERH | ||||||
Compositional bias | 1552-1571 | Polar residues | ||||
Sequence: AEPSAGTNKRSSVISAGGSI | ||||||
Compositional bias | 1612-1626 | Polar residues | ||||
Sequence: NLPSDGSNSSSTNDD | ||||||
Compositional bias | 1649-1668 | Polar residues | ||||
Sequence: FRNGPQQQSSLPRQDPLFHS |
Keywords
- Technical term