A0A8J2HH82 · A0A8J2HH82_COTCN

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentearly endosome membrane
Cellular Componentendoplasmic reticulum membrane
Cellular Componentextracellular region
Cellular ComponentGolgi membrane
Cellular Componentmultivesicular body membrane
Cellular Componentplasma membrane
Cellular Componentrecycling endosome membrane
Cellular Componenttransport vesicle membrane
Biological Processendocytosis
Biological Processpost-Golgi vesicle-mediated transport
Biological Processvacuolar transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Sortilin-related receptor
  • Alternative names
    • Low-density lipoprotein receptor relative with 11 ligand-binding repeats
    • Sorting protein-related receptor containing LDLR class A repeats

Gene names

    • ORF names
      HICCMSTLAB_LOCUS8732

Organism names

Accessions

  • Primary accession
    A0A8J2HH82

Proteomes

Subcellular Location

Cell membrane
; Single-pass membrane protein
Cytoplasmic vesicle, secretory vesicle membrane
; Single-pass type I membrane protein
Early endosome membrane
; Single-pass type I membrane protein
Endoplasmic reticulum membrane
; Single-pass type I membrane protein
Endosome, multivesicular body membrane
; Single-pass type I membrane protein
Golgi apparatus, trans-Golgi network membrane
; Single-pass type I membrane protein
Recycling endosome membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane2093-2116Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-27
ChainPRO_503528960428-2169
Disulfide bond1097↔1109
Disulfide bond1104↔1122
Disulfide bond1116↔1131
Disulfide bond1136↔1148
Disulfide bond1143↔1161
Disulfide bond1155↔1170
Disulfide bond1175↔1187
Disulfide bond1182↔1200
Disulfide bond1194↔1209
Disulfide bond1218↔1230
Disulfide bond1225↔1243
Disulfide bond1237↔1252
Disulfide bond1283↔1298
Disulfide bond1316↔1328
Disulfide bond1323↔1341
Disulfide bond1335↔1350
Disulfide bond1372↔1384
Disulfide bond1379↔1397
Disulfide bond1391↔1406
Disulfide bond1433↔1448
Disulfide bond1460↔1472
Disulfide bond1467↔1485
Disulfide bond1479↔1494

Keywords

Family & Domains

Features

Showing features for repeat, domain.

TypeIDPosition(s)Description
Repeat905-950LDL-receptor class B
Repeat951-995LDL-receptor class B
Domain1503-1599Fibronectin type-III
Domain1603-1692Fibronectin type-III
Domain1697-1786Fibronectin type-III
Domain1789-1882Fibronectin type-III
Domain1980-2081Fibronectin type-III

Sequence similarities

Belongs to the VPS10-related sortilin family. SORL1 subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,169
  • Mass (Da)
    245,456
  • Last updated
    2022-05-25 v1
  • Checksum
    07BF337B76A137CF
MAARVISGFYQLTLILHLFLFINFNNGENSYENSRTLYVTDNDQSLRQKRSFIIDKNDYFGDDNDDETLGRFRRDVPQTPTPSGFSNSSSNITVKLNFLDDPHQQLMVHWVGEKSNVIICLARDNTNPRDKPTQKLNPSSVYISYDYGDTFENKSELFKINSIPVEYATLDKFYNHPKFNTYCVFADSANSVIFTTNNNGKTINKSSVPFHPSEILFYEDNPLYFLALDKIDPRRTLWMTSDLGKTWLRIHESVKAFYWSNSSPKTIIIVRDEFKGSTVVELDLTFDQNQRRDLRSVLIKNVEDFQIRGDYMFATKKSVVDPSANETAQSLDLYVSFKNQTFVMAHFDTELERKQYHIADVSNNRIFVAVAHTDTLINLYISEVVDHTMARFILSLKGIFTHFPNSTWKGSWVNELAEEAFTDLYKVEGLRGIYIVSHIKENFKGNSVGPEYLESLITFDHGVTWNKIKPPENVKHENVPDSTWSLHLSQRFSQLYPVTRSVTIMSSKSAPGIIMATGVLGSSLKGHPALYVSRDAGLTWKQVLKDFYFFNMGDHGGVLVAVKYFKTRGETRDISYSIDEGATWQTYQFNQEMLRVYGLMTEPGENTTVFTMFGSTSGLHKWLIIKVDLRNAFEKECKDDDFKFWSPASSNQPGMSCILGRREVYKRRAASVKCYTGVDYDRPISFEICPCDFQDYQCDYGFIKSGSPAHCIKNNALVHYDPYKVPSLCFPGKFYNRTKGYRKIPDDDCSGGYAKKFEPDEIPCPIVEPQEFLLVAQREHISRIDIRSHSLEVLPVHDLKNVIAIEYDVKNNCLYWADIVNDTIGRQCFKDGTSYPEILVETDLSSVEGMAYDWVSKVLYFVDGVKMRIQIIRTDLTMAGRMRRTILGSNNLQKPRGIAVHPMMGYMFWTDWAPGNASVSRANLDGTDIKRLFTKGTVEWPNGICIDFIAERIYWVDAREDYIGSSDYDGKRFKKVITTDDRVSHPFAVAVFKENMYWDDWKQSMIFVADKDHGAGITTPLGTLSGLMDLKIFAHSVQTGTNKCENSTCSHLCLGAPNDGFVCLCPDGMVMTDGKCMCPGGIKPFANSTCPRVASTCASNQFACGNGVCISGFWKCDGDNDCGDNSDEVNCKKATCSPNNFECDDDKCIPRFWMCDLDKDCNDGRDELNCTYLNCTDTQFKCDNGRCISHRWQCDGEDDCRDGSDERHCNKSAVPNTCKTDEIACSDNTCVPKSWECDDENDCDDGADEKECVSRGCHDWQFACNTIEDGHTAHKCIYKAWLCDGDRDCHDGSDEDHCPSPPPEPPTPSALPTNTCNDWMFKCNNTKCVPYWWKCDSVDDCGDASDELGCGVPPDEPETPYITESPKLPRICRDNQFQCYDGQCIDDSWICDGTPDCKLGEDELRCDHTRTGCRPDQFMCRTDGSCIPLTNICNGVLDCPDRSDEASCDIHQTEPPTTFCQTGSFLCDENKCIPLAFYCDGKHDCVDGFDELHCDKNNSRVYQVMVLEFDERLTNATSLYLNWHKPIPSNTTLEFLPSLAKVEPNAKWINATGWIKDNRYQFNNLEPYTPYNLTVYVRQEGQTTVYPPFKYWIIKTDQGIPSEPWNVTVVQKNGTRVELSWRPPQHPNGIITGYEAYVTPPIPPAPFPLQKTSYTFDLPFEPNKTYSFWVIAKNRKYDSKPSAVAELVFDGAANIDDIQYLKVIETTNNSVHLTWAALKGVDGYHITPRAPPPYPSYHTLNTTQNDFVVTNLSPGTPYTFEVNAMKKSYIGKVVMIAATTKDTPLPSVPNLNAESKKLDGTTVKLSWDQPKSTRKIRWQYAIHYALNMQDLFKDYKILTPNKSASIKNLEACETYMFAVGVRGNGYGAGPLSQPVQVDTYYNVKAPPKQLRVTPAPKTTDSIIVSWSASCMKIDDPIIYRLTVTEMTLNEKSTVILPPTNETVIKHTFTGIKYGGKYKITVASNVTDAIESQPVVYQAAPLTPPHQIRVEAKDGKFTVNWEEPMNSDNMKNDTKRHYQVLVNENTRAFNESTAKVYNVDRPPFIFTEAKVNSMYLFTVKLITDKGYQSGISEIVGVQIPLTADWPGTINTSSILSFAIPICLLVIALGVGFAYFFVRHRRLSNNFTLFANSHYDTRRGQATFPGTTDALDEEDSPVIRGFSDDEPLVIA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAJNRD030001121
EMBL· GenBank· DDBJ
CAG5097487.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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