A0A8J2HH82 · A0A8J2HH82_COTCN
- ProteinSortilin-related receptor
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2169 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | early endosome membrane | |
Cellular Component | endoplasmic reticulum membrane | |
Cellular Component | extracellular region | |
Cellular Component | Golgi membrane | |
Cellular Component | multivesicular body membrane | |
Cellular Component | plasma membrane | |
Cellular Component | recycling endosome membrane | |
Cellular Component | transport vesicle membrane | |
Biological Process | endocytosis | |
Biological Process | post-Golgi vesicle-mediated transport | |
Biological Process | vacuolar transport |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSortilin-related receptor
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Ichneumonoidea > Braconidae > Microgastrinae > Cotesia
Accessions
- Primary accessionA0A8J2HH82
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass membrane protein
Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass type I membrane protein
Early endosome membrane ; Single-pass type I membrane protein
Endoplasmic reticulum membrane ; Single-pass type I membrane protein
Endosome, multivesicular body membrane ; Single-pass type I membrane protein
Golgi apparatus, trans-Golgi network membrane ; Single-pass type I membrane protein
Recycling endosome membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 2093-2116 | Helical | ||||
Sequence: ILSFAIPICLLVIALGVGFAYFFV |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-27 | |||||
Sequence: MAARVISGFYQLTLILHLFLFINFNNG | ||||||
Chain | PRO_5035289604 | 28-2169 | Sortilin-related receptor | |||
Sequence: ENSYENSRTLYVTDNDQSLRQKRSFIIDKNDYFGDDNDDETLGRFRRDVPQTPTPSGFSNSSSNITVKLNFLDDPHQQLMVHWVGEKSNVIICLARDNTNPRDKPTQKLNPSSVYISYDYGDTFENKSELFKINSIPVEYATLDKFYNHPKFNTYCVFADSANSVIFTTNNNGKTINKSSVPFHPSEILFYEDNPLYFLALDKIDPRRTLWMTSDLGKTWLRIHESVKAFYWSNSSPKTIIIVRDEFKGSTVVELDLTFDQNQRRDLRSVLIKNVEDFQIRGDYMFATKKSVVDPSANETAQSLDLYVSFKNQTFVMAHFDTELERKQYHIADVSNNRIFVAVAHTDTLINLYISEVVDHTMARFILSLKGIFTHFPNSTWKGSWVNELAEEAFTDLYKVEGLRGIYIVSHIKENFKGNSVGPEYLESLITFDHGVTWNKIKPPENVKHENVPDSTWSLHLSQRFSQLYPVTRSVTIMSSKSAPGIIMATGVLGSSLKGHPALYVSRDAGLTWKQVLKDFYFFNMGDHGGVLVAVKYFKTRGETRDISYSIDEGATWQTYQFNQEMLRVYGLMTEPGENTTVFTMFGSTSGLHKWLIIKVDLRNAFEKECKDDDFKFWSPASSNQPGMSCILGRREVYKRRAASVKCYTGVDYDRPISFEICPCDFQDYQCDYGFIKSGSPAHCIKNNALVHYDPYKVPSLCFPGKFYNRTKGYRKIPDDDCSGGYAKKFEPDEIPCPIVEPQEFLLVAQREHISRIDIRSHSLEVLPVHDLKNVIAIEYDVKNNCLYWADIVNDTIGRQCFKDGTSYPEILVETDLSSVEGMAYDWVSKVLYFVDGVKMRIQIIRTDLTMAGRMRRTILGSNNLQKPRGIAVHPMMGYMFWTDWAPGNASVSRANLDGTDIKRLFTKGTVEWPNGICIDFIAERIYWVDAREDYIGSSDYDGKRFKKVITTDDRVSHPFAVAVFKENMYWDDWKQSMIFVADKDHGAGITTPLGTLSGLMDLKIFAHSVQTGTNKCENSTCSHLCLGAPNDGFVCLCPDGMVMTDGKCMCPGGIKPFANSTCPRVASTCASNQFACGNGVCISGFWKCDGDNDCGDNSDEVNCKKATCSPNNFECDDDKCIPRFWMCDLDKDCNDGRDELNCTYLNCTDTQFKCDNGRCISHRWQCDGEDDCRDGSDERHCNKSAVPNTCKTDEIACSDNTCVPKSWECDDENDCDDGADEKECVSRGCHDWQFACNTIEDGHTAHKCIYKAWLCDGDRDCHDGSDEDHCPSPPPEPPTPSALPTNTCNDWMFKCNNTKCVPYWWKCDSVDDCGDASDELGCGVPPDEPETPYITESPKLPRICRDNQFQCYDGQCIDDSWICDGTPDCKLGEDELRCDHTRTGCRPDQFMCRTDGSCIPLTNICNGVLDCPDRSDEASCDIHQTEPPTTFCQTGSFLCDENKCIPLAFYCDGKHDCVDGFDELHCDKNNSRVYQVMVLEFDERLTNATSLYLNWHKPIPSNTTLEFLPSLAKVEPNAKWINATGWIKDNRYQFNNLEPYTPYNLTVYVRQEGQTTVYPPFKYWIIKTDQGIPSEPWNVTVVQKNGTRVELSWRPPQHPNGIITGYEAYVTPPIPPAPFPLQKTSYTFDLPFEPNKTYSFWVIAKNRKYDSKPSAVAELVFDGAANIDDIQYLKVIETTNNSVHLTWAALKGVDGYHITPRAPPPYPSYHTLNTTQNDFVVTNLSPGTPYTFEVNAMKKSYIGKVVMIAATTKDTPLPSVPNLNAESKKLDGTTVKLSWDQPKSTRKIRWQYAIHYALNMQDLFKDYKILTPNKSASIKNLEACETYMFAVGVRGNGYGAGPLSQPVQVDTYYNVKAPPKQLRVTPAPKTTDSIIVSWSASCMKIDDPIIYRLTVTEMTLNEKSTVILPPTNETVIKHTFTGIKYGGKYKITVASNVTDAIESQPVVYQAAPLTPPHQIRVEAKDGKFTVNWEEPMNSDNMKNDTKRHYQVLVNENTRAFNESTAKVYNVDRPPFIFTEAKVNSMYLFTVKLITDKGYQSGISEIVGVQIPLTADWPGTINTSSILSFAIPICLLVIALGVGFAYFFVRHRRLSNNFTLFANSHYDTRRGQATFPGTTDALDEEDSPVIRGFSDDEPLVIA | ||||||
Disulfide bond | 1097↔1109 | |||||
Sequence: CASNQFACGNGVC | ||||||
Disulfide bond | 1104↔1122 | |||||
Sequence: CGNGVCISGFWKCDGDNDC | ||||||
Disulfide bond | 1116↔1131 | |||||
Sequence: CDGDNDCGDNSDEVNC | ||||||
Disulfide bond | 1136↔1148 | |||||
Sequence: CSPNNFECDDDKC | ||||||
Disulfide bond | 1143↔1161 | |||||
Sequence: CDDDKCIPRFWMCDLDKDC | ||||||
Disulfide bond | 1155↔1170 | |||||
Sequence: CDLDKDCNDGRDELNC | ||||||
Disulfide bond | 1175↔1187 | |||||
Sequence: CTDTQFKCDNGRC | ||||||
Disulfide bond | 1182↔1200 | |||||
Sequence: CDNGRCISHRWQCDGEDDC | ||||||
Disulfide bond | 1194↔1209 | |||||
Sequence: CDGEDDCRDGSDERHC | ||||||
Disulfide bond | 1218↔1230 | |||||
Sequence: CKTDEIACSDNTC | ||||||
Disulfide bond | 1225↔1243 | |||||
Sequence: CSDNTCVPKSWECDDENDC | ||||||
Disulfide bond | 1237↔1252 | |||||
Sequence: CDDENDCDDGADEKEC | ||||||
Disulfide bond | 1283↔1298 | |||||
Sequence: CDGDRDCHDGSDEDHC | ||||||
Disulfide bond | 1316↔1328 | |||||
Sequence: CNDWMFKCNNTKC | ||||||
Disulfide bond | 1323↔1341 | |||||
Sequence: CNNTKCVPYWWKCDSVDDC | ||||||
Disulfide bond | 1335↔1350 | |||||
Sequence: CDSVDDCGDASDELGC | ||||||
Disulfide bond | 1372↔1384 | |||||
Sequence: CRDNQFQCYDGQC | ||||||
Disulfide bond | 1379↔1397 | |||||
Sequence: CYDGQCIDDSWICDGTPDC | ||||||
Disulfide bond | 1391↔1406 | |||||
Sequence: CDGTPDCKLGEDELRC | ||||||
Disulfide bond | 1433↔1448 | |||||
Sequence: CNGVLDCPDRSDEASC | ||||||
Disulfide bond | 1460↔1472 | |||||
Sequence: CQTGSFLCDENKC | ||||||
Disulfide bond | 1467↔1485 | |||||
Sequence: CDENKCIPLAFYCDGKHDC | ||||||
Disulfide bond | 1479↔1494 | |||||
Sequence: CDGKHDCVDGFDELHC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for repeat, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 905-950 | LDL-receptor class B | ||||
Sequence: GYMFWTDWAPGNASVSRANLDGTDIKRLFTKGTVEWPNGICIDFIA | ||||||
Repeat | 951-995 | LDL-receptor class B | ||||
Sequence: ERIYWVDAREDYIGSSDYDGKRFKKVITTDDRVSHPFAVAVFKEN | ||||||
Domain | 1503-1599 | Fibronectin type-III | ||||
Sequence: QVMVLEFDERLTNATSLYLNWHKPIPSNTTLEFLPSLAKVEPNAKWINATGWIKDNRYQFNNLEPYTPYNLTVYVRQEGQTTVYPPFKYWIIKTDQG | ||||||
Domain | 1603-1692 | Fibronectin type-III | ||||
Sequence: EPWNVTVVQKNGTRVELSWRPPQHPNGIITGYEAYVTPPIPPAPFPLQKTSYTFDLPFEPNKTYSFWVIAKNRKYDSKPSAVAELVFDGA | ||||||
Domain | 1697-1786 | Fibronectin type-III | ||||
Sequence: DIQYLKVIETTNNSVHLTWAALKGVDGYHITPRAPPPYPSYHTLNTTQNDFVVTNLSPGTPYTFEVNAMKKSYIGKVVMIAATTKDTPLP | ||||||
Domain | 1789-1882 | Fibronectin type-III | ||||
Sequence: PNLNAESKKLDGTTVKLSWDQPKSTRKIRWQYAIHYALNMQDLFKDYKILTPNKSASIKNLEACETYMFAVGVRGNGYGAGPLSQPVQVDTYYN | ||||||
Domain | 1980-2081 | Fibronectin type-III | ||||
Sequence: PLTPPHQIRVEAKDGKFTVNWEEPMNSDNMKNDTKRHYQVLVNENTRAFNESTAKVYNVDRPPFIFTEAKVNSMYLFTVKLITDKGYQSGISEIVGVQIPLT |
Sequence similarities
Belongs to the VPS10-related sortilin family. SORL1 subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,169
- Mass (Da)245,456
- Last updated2022-05-25 v1
- Checksum07BF337B76A137CF
Keywords
- Technical term