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A0A8J2FNZ1 · A0A8J2FNZ1_9BACT

Function

function

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site203Tele-phosphohistidine intermediate
Binding site310phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site346phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site446Mg2+ (UniProtKB | ChEBI)
Binding site469-470phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site470Mg2+ (UniProtKB | ChEBI)
Binding site480phosphoenolpyruvate (UniProtKB | ChEBI)
Active site517Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionkinase activity
Molecular Functionmetal ion binding
Molecular Functionphosphoenolpyruvate-protein phosphotransferase activity
Biological Processphosphoenolpyruvate-dependent sugar phosphotransferase system
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoenolpyruvate-protein phosphotransferase
  • EC number
  • Alternative names
    • Phosphotransferase system, enzyme I

Gene names

    • Name
      ptsI
    • ORF names
      MPNT_30074

Organism names

Accessions

  • Primary accession
    A0A8J2FNZ1

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, coiled coil.

Type
IDPosition(s)Description
Domain17-140Phosphotransferase system enzyme I N-terminal
Coiled coil54-81
Domain167-239PEP-utilising enzyme mobile
Domain266-556PEP-utilising enzyme C-terminal

Sequence similarities

Belongs to the PEP-utilizing enzyme family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    610
  • Mass (Da)
    68,247
  • Last updated
    2022-05-25 v1
  • MD5 Checksum
    E04FF9B60A29DF45363396D1A4A4A772
MEVDNVSQGTTAEMVLRGIPASPGLAIGPAVLLQEGRVKVPRWKIRPEEIRGELERLQAALLETRRELLEAKAKLAENESQGAASVLDVHLMVLEDPAILEALKARLEEKLYNVEYVYHEITEEFSQHLLALNEDYFRERASDIRDVARRVLAHCQGNPSLARWQLEEPSILAARSLYLSDVVALDRRALLGLITEEGTRTSHAAILARSLNIPAVVGLGGLLKHLNDQVEILVDGVEGWVVIRPSESTKRRLLERQMRRNHLEARLNLSRDLTAVTRDGRHITVSANVELPDDIPLVRANGAEGIGLLRTEFLFLNRATPPSEEEQCAAYREIAQAVKPHGVIIRTLDLGADKLGPLLPNPVREANPFLGWRGIRLSLDCRNLFQTQLRAIWRAGTEGNVRVMFPMVTTLEELRLAKELFWQCRQQLCEEGVPVPEQIECGVMVEVPSVALLADLFAREVDFFSVGTNDLVQYTLAVDRLNGKVSALYQPTHPSVLRLLHRVVEEAHRFHIWVGVCGEMAADLFSALALVALGVDELSMGSVFVPWIKDAIRHVHYGELRKHVDELTQCPTSGDVLERLRELAQLYFPHLLEEENQWEAGGLSPSIPGT

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAJNOB010000023
EMBL· GenBank· DDBJ
CAF0698948.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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