Essential maintenance is planned to begin on Tue Jan 28 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ during this time.

A0A8J1N1U8 · A0A8J1N1U8_XENLA

Function

Catalytic activity

Features

Showing features for binding site.

1724100200300400500600700
TypeIDPosition(s)Description
Binding site92ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentdendrite
Molecular FunctionATP binding
Molecular Functionprotein serine/threonine kinase activity
Molecular Functiontau-protein kinase activity
Biological Processintracellular signal transduction
Biological Processmicrotubule cytoskeleton organization
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • Name
      mark2.S
    • Synonyms
      emk-1
      , emk1
      , mark2
      , par-1
      , par1
      , par1b
      , xpar-1b

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus

Accessions

  • Primary accession
    A0A8J1N1U8

Proteomes

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for region, domain, compositional bias.

Type
IDPosition(s)Description
Region24-43Disordered
Domain63-314Protein kinase
Domain333-372UBA
Region381-581Disordered
Compositional bias393-417Polar residues
Compositional bias424-440Polar residues
Compositional bias441-456Basic and acidic residues
Compositional bias471-497Polar residues
Compositional bias508-581Polar residues
Domain675-724KA1

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    724
  • Mass (Da)
    81,207
  • Last updated
    2022-05-25 v1
  • MD5 Checksum
    AA7CD10D785EA9FFFAC8D7BD02EDF1D9
MLEDLAAKHRDQQDSCINPLAAHEPALGHADPKTSSSSNKPNMLRSRTSIAATADEQPHIGNYRLLKTIGKGNFAKVKLARHVLTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVNLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKLIVHRDLKAENLLLDSDMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMRDRWMNVGHEEDELKPYVEPIPDYKDPKRTELMVTMGYTNEEITDSLVNQKYNEVMATYLLLGYKSSEMDNDHLTLKPRPPPGVSNNIVSSPAHKVQRSVSANPKQRRPGDQAGQAIPKSNSYSKKTQSNNAENRRSADEKESGRKSGSTVRVPPSPLSGLDRKKTTPTPSTNSVLSTGTNRSRNSPMLDRATLVPGSIHNGKDSTAPQRLPVSSPSAHNISSAATERNNFPRGVSSRSTFHAGQVRQARDQQNLGFVSPASPSGISQGRRGATGSIFSKFTSKFVRKNLSFRFPRRPHLSVVDKEKDKEDLRDSKPRSLRFTWSMKTTSSMEPNEMISEICKVLDANNCQYESQDKYMLLCVHGTPGHDNYVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANDLKL

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8J1N118A0A8J1N118_XENLAmark2.S789
A0A8J1MZF3A0A8J1MZF3_XENLAmark2.S765
A0A8J1MZ62A0A8J1MZ62_XENLAmark2.S730
A0A8J1N123A0A8J1N123_XENLAmark2.S739
A0A8J1N0B4A0A8J1N0B4_XENLAmark2.S774
A0A8J1N0C0A0A8J1N0C0_XENLAmark2.S715
A0A8J1N1U1A0A8J1N1U1_XENLAmark2.S782
Q804T1Q804T1_XENLAmark2.S780

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias393-417Polar residues
Compositional bias424-440Polar residues
Compositional bias441-456Basic and acidic residues
Compositional bias471-497Polar residues
Compositional bias508-581Polar residues

Keywords

Sequence databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help