A0A8I6GLM9 · A0A8I6GLM9_RAT
- ProteinAlkylglycerone-phosphate synthase
- GeneAgps
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids602 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
Catalytic activity
- a 1-acylglycerone 3-phosphate + a long chain fatty alcohol = 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H+
Cofactor
Pathway
Glycerolipid metabolism; ether lipid biosynthesis.
Features
Showing features for binding site, site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 178-184 | FAD (UniProtKB | ChEBI) | ||||
Sequence: PIGGGTS | ||||||
Binding site | 247-253 | FAD (UniProtKB | ChEBI) | ||||
Sequence: DSLEFST | ||||||
Binding site | 260-263 | FAD (UniProtKB | ChEBI) | ||||
Sequence: TRAS | ||||||
Binding site | 312-318 | FAD (UniProtKB | ChEBI) | ||||
Sequence: EGTLGVI | ||||||
Site | 363 | Important for enzyme activity | ||||
Sequence: R | ||||||
Binding site | 459 | substrate | ||||
Sequence: R | ||||||
Active site | 522 | Proton donor/acceptor | ||||
Sequence: Y |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | alkylglycerone-phosphate synthase activity | |
Molecular Function | FAD binding | |
Biological Process | ether lipid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlkylglycerone-phosphate synthase
- EC number
- Short namesAlkyl-DHAP synthase
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A8I6GLM9
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 146-328 | FAD-binding PCMH-type | ||||
Sequence: FERIPDIVVWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQDLERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNVYGNIEDLVVHMKMVTPRGVIEKSSQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPT |
Sequence similarities
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length602
- Mass (Da)67,571
- Last updated2022-05-25 v1
- ChecksumF5F3886647E0763D
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q9EQR2 | ADAS_RAT | Agps | 644 | ||
A0A8I5ZN98 | A0A8I5ZN98_RAT | Agps | 670 | ||
F1M9Q8 | F1M9Q8_RAT | Agps | 620 |
Keywords
- Technical term