A0A8I6GLM9 · A0A8I6GLM9_RAT

  • Protein
    Alkylglycerone-phosphate synthase
  • Gene
    Agps
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Glycerolipid metabolism; ether lipid biosynthesis.

Features

Showing features for binding site, site, active site.

160250100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site178-184FAD (UniProtKB | ChEBI)
Binding site247-253FAD (UniProtKB | ChEBI)
Binding site260-263FAD (UniProtKB | ChEBI)
Binding site312-318FAD (UniProtKB | ChEBI)
Site363Important for enzyme activity
Binding site459substrate
Active site522Proton donor/acceptor

GO annotations

AspectTerm
Cellular Componentperoxisome
Molecular Functionalkylglycerone-phosphate synthase activity
Molecular FunctionFAD binding
Biological Processether lipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alkylglycerone-phosphate synthase
  • EC number
  • Short names
    Alkyl-DHAP synthase

Gene names

    • Name
      Agps

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I6GLM9

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain146-328FAD-binding PCMH-type

Sequence similarities

Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    602
  • Mass (Da)
    67,571
  • Last updated
    2022-05-25 v1
  • Checksum
    F5F3886647E0763D
MSITLSTAEPPLAPGQRVYVCIYTCVFFLIRQELMKWNGWGYNDSKFLLNKKGQVELTGKRYPLSGLALPTLKDWIQNTLGVNLEHKTTSKPSINPSEAPPSIVNEDFLQELKEAHISYSQDADDRVFRAHGHCLHEIFLLREGMFERIPDIVVWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQDLERQLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNVYGNIEDLVVHMKMVTPRGVIEKSSQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREIAKQRCAPASIRLMDNQQFQFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQISVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQRGYLLTYVIAYMRDLGLEYYVVGESFETSAPWDRVIDLCRNVKERIRRECKERGVQFAPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAARDEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPSNIFGNRNLL

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9EQR2ADAS_RATAgps644
A0A8I5ZN98A0A8I5ZN98_RATAgps670
F1M9Q8F1M9Q8_RATAgps620

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp