A0A8I6GH61 · A0A8I6GH61_RAT

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxon
Cellular Componentcaveola
Cellular Componentcell surface
Cellular Componentdendrite
Cellular Componentextracellular space
Cellular Componentglutamatergic synapse
Cellular Componentmicrotubule associated complex
Cellular Componentneuronal cell body
Cellular Componentplasma membrane
Cellular Componentpostsynaptic density membrane
Cellular Componentreceptor complex
Cellular ComponentSchaffer collateral - CA1 synapse
Molecular Functionamyloid-beta binding
Molecular Functionapolipoprotein binding
Molecular Functioncalcium ion binding
Molecular Functioncalcium-dependent protein binding
Molecular Functionhigh-density lipoprotein particle binding
Molecular Functionkinesin binding
Molecular Functionreelin receptor activity
Molecular Functionvery-low-density lipoprotein particle receptor activity
Biological Processammon gyrus development
Biological Processcellular response to cholesterol
Biological Processcellular response to growth factor stimulus
Biological Processcerebral cortex development
Biological Processchemical synaptic transmission
Biological Processdendrite morphogenesis
Biological Processendocytosis
Biological Processhippocampus development
Biological Processlayer formation in cerebral cortex
Biological Processmodulation of chemical synaptic transmission
Biological Processpositive regulation of dendrite development
Biological Processpositive regulation of dendritic spine morphogenesis
Biological Processpositive regulation of peptidyl-tyrosine phosphorylation
Biological Processreelin-mediated signaling pathway
Biological Processregulation of apoptotic process
Biological Processregulation of innate immune response
Biological Processresponse to xenobiotic stimulus
Biological Processventral spinal cord development

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • LDL receptor related protein 8

Gene names

    • Name
      Lrp8

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I6GH61

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane735-758Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-31
ChainPRO_503530393732-873
Disulfide bond44↔56
Disulfide bond51↔69
Disulfide bond63↔78
Disulfide bond83↔95
Disulfide bond90↔108
Disulfide bond145↔160
Disulfide bond168↔180
Disulfide bond175↔193
Disulfide bond187↔202
Disulfide bond216↔234
Disulfide bond290↔300

Keywords

Family & Domains

Features

Showing features for domain, repeat, region.

TypeIDPosition(s)Description
Domain286-325EGF-like
Repeat372-418LDL-receptor class B
Repeat419-461LDL-receptor class B
Repeat462-505LDL-receptor class B
Repeat506-550LDL-receptor class B
Region665-728Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    873
  • Mass (Da)
    96,766
  • Last updated
    2022-05-25 v1
  • Checksum
    67302E6EBC7588C0
MGRPERGALRPLALLLLLLLLLLQLQHLSTADPLPGGQGPVKECEEDQFRCRNERCIPSVWRCDEDNDCSDNSDEDDCPKRTCTDSDFTCDNGHCIPERWKCDGEEECPDGSDESKATCSSEECPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCPTSAPGPCRENDFQCGDGTCILAIKRCNQERDCLDGSDEAGCLQESTCEGPRRFQCKSGECVDGGKVCDDQRDCRDWSDEPQKVCGLNECLHNNGGCSHICTDLKIGFECTCPAGFQLLDQKTCGDIDECQDPDACSQICVNYKGYFKCECHPGYEMDTLTKNCKAVAGRSPSLIFTNRHEVRRIDLVKRDYSRLIPMLKNVVALDVEVDTNRIYWCDLSYRKIYSAHMDKASIPDEQVVLIGEQLHSPEGLAVDWVHKHIYWTDSGNKTVSVATTDGRRRCTLFNRDLSEPRAIAVDPLRGFMYWSDWGFQAKIEKAGLNGADRQTLVSDNIEWPNGITLDLLSQRLYWVDSKLHQLSSIDFNGGNRKMLIFSTDFLSHPFGVAVFEDKVFWTDLENEAIFSANRLNGLEISILAENLNNPHDIVIFHELKQPKAADACELSAQPNGGCEYLCLPAPQISSHSPKYTCACPDTMWLGPDMKRCYRAPPSTSTTTLASAMTRTVPATTGAPGTTIHDSTYQNHSTEMPSQTAAVPHSVNIPKAHSTSPSTLSPATSNHSQHYGNEGSQMGSTVTAAVIGIIVPIVVIALLCMSGYLIWRNWKRKNTKSMNFDNPVYRKTTEEEEEDELHIGRTAQIGHVYPAAISSYDRPLWAEPCLGETRDLEDPAPAHKELFVLPGEPRSQLHQLPKNPLSELPVVKCKRVALSLEDDGLP

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8I5ZTA7A0A8I5ZTA7_RATLrp8958
A0A8I6ALZ7A0A8I6ALZ7_RATLrp8972
D3ZE75D3ZE75_RATLrp8999
A0A8I6AE51A0A8I6AE51_RATLrp8697
A0A8I6GFL9A0A8I6GFL9_RATLrp8913
A0A8I6A6L0A0A8I6A6L0_RATLrp8729
A0A8I5ZVL7A0A8I5ZVL7_RATLrp8790

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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