A0A8I6GH02 · A0A8I6GH02_RAT

  • Protein
    Contactin associated protein 2
  • Gene
    Cntnap2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxolemma
Cellular Componentaxon
Cellular Componentaxon initial segment
Cellular Componentcell surface
Cellular Componentcerebellar granule cell to Purkinje cell synapse
Cellular Componentdendrite
Cellular Componentearly endosome
Cellular Componentexcitatory synapse
Cellular ComponentGABA-ergic synapse
Cellular Componentglutamatergic synapse
Cellular ComponentGolgi apparatus
Cellular Componentjuxtaparanode region of axon
Cellular Componentmembrane
Cellular Componentneuron projection
Cellular Componentneuron spine
Cellular Componentneuronal cell body
Cellular Componentparanodal junction
Cellular Componentparanode region of axon
Cellular Componentplasma membrane raft
Cellular Componentpostsynapse
Cellular Componentpresynapse
Cellular Componentpresynaptic active zone membrane
Cellular Componentpresynaptic membrane
Cellular Componentsynapse
Cellular Componentsynaptic membrane
Cellular Componentvoltage-gated potassium channel complex
Molecular Functionenzyme binding
Molecular FunctionPDZ domain binding
Molecular Functionprotease binding
Molecular Functiontransmembrane transporter binding
Biological Processaction potential initiation
Biological Processadult behavior
Biological Processassociative learning
Biological Processaxonogenesis
Biological Processbehavioral response to pain
Biological Processcell adhesion
Biological Processcell morphogenesis
Biological Processcell population proliferation
Biological Processcentral nervous system myelination
Biological Processcerebellar Purkinje cell layer morphogenesis
Biological Processcerebellum development
Biological Processcerebral cortex development
Biological Processchemical synaptic transmission
Biological Processcircadian sleep/wake cycle
Biological Processclustering of voltage-gated potassium channels
Biological Processdendrite arborization
Biological Processdendritic spine development
Biological Processdendritic spine maintenance
Biological Processdendritic spine organization
Biological Processembryonic brain development
Biological ProcessERK1 and ERK2 cascade
Biological Processexcitatory chemical synaptic transmission
Biological Processexcitatory postsynaptic potential
Biological Processexcitatory synapse assembly
Biological Processfat cell differentiation
Biological Processgene expression
Biological Processglial cell proliferation
Biological Processglutamatergic neuron differentiation
Biological Processgrooming behavior
Biological Processin utero embryonic development
Biological Processinflammatory response
Biological Processinhibitory chemical synaptic transmission
Biological Processinhibitory synapse assembly
Biological Processintracellular signal transduction
Biological Processlearning
Biological Processlimbic system development
Biological Processlocomotor rhythm
Biological Processlocomotory behavior
Biological Processmaintenance of synapse structure
Biological Processmitochondrion organization
Biological Processmotor behavior
Biological Processmulticellular organism growth
Biological Processmyelination
Biological Processnegative regulation of neuronal action potential
Biological Processnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processnegative regulation of synaptic transmission, GABAergic
Biological Processneural precursor cell proliferation
Biological Processneuromuscular junction development, skeletal muscle fiber
Biological Processneuromuscular process
Biological Processneuromuscular process controlling posture
Biological Processneuron projection development
Biological Processneuron projection morphogenesis
Biological Processneuronal action potential
Biological Processpositive regulation of gap junction assembly
Biological Processpositive regulation of neuronal action potential
Biological Processpostsynaptic density organization
Biological Processprepulse inhibition
Biological Processprotein localization
Biological Processprotein localization to juxtaparanode region of axon
Biological Processregulation of postsynaptic membrane neurotransmitter receptor levels
Biological Processresponse to dietary excess
Biological Processresponse to heat
Biological Processresponse to hormone
Biological Processresponse to interleukin-17
Biological Processresponse to light intensity
Biological Processresponse to mechanical stimulus
Biological Processresponse to metformin
Biological Processresponse to odorant
Biological Processresponse to pain
Biological Processresponse to xenobiotic stimulus
Biological Processrhythmic behavior
Biological Processsocial behavior
Biological Processstartle response
Biological Processstriatum development
Biological Processsuperior temporal gyrus development
Biological Processthalamus development
Biological ProcessTOR signaling
Biological Processtransmission of nerve impulse
Biological Processvocal learning
Biological Processvocalization behavior
Biological Processwalking behavior

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Contactin associated protein 2

Gene names

    • Name
      Cntnap2
    • Synonyms
      AABR07060487.1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I6GH02

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-27
ChainPRO_503518217628-1332
Disulfide bond936↔963

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain35-181F5/8 type C
Domain187-368Laminin G
Domain373-552Laminin G
Domain554-591EGF-like
Domain590-642Fibrinogen C-terminal
Domain799-963Laminin G
Domain964-1002EGF-like
Domain1021-1215Laminin G

Sequence similarities

Belongs to the neurexin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,332
  • Mass (Da)
    148,162
  • Last updated
    2022-05-25 v1
  • Checksum
    7B6FC914B2C7ED7F
MVISLRAGCRAALSLWILSSFICRAWTAPSSFQKCDEPLVSGLPHVSFSSSSSLSSSYAPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNVNSDSVVRHDLQHAVVARYVRIVPLDWNGEGHIGLRAEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALKFKTSESEGVLLHGEGQQGDYITLELKKAKLVFSLNLGSNQLGPIYGHTSVTSGSLLDDHHWHSVLIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSNRKNFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFACVEPYTVPVFFNATSYLEVPGRLNQDLFSVSFQFRTWNPSGLLLFSHFADNLGNVEIDLVESKVGVHINTTQTKTSQIDISSGSGLNDGQWHEVRFLAKENFAVLTIDGDEASAVRTNSPLQVKTGERYYFGGFLNHMNNASHSALQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVTIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTEDKVWTIVSHDLQMQTTVVGYNPEKYSVTQLIYSASMDQISAITSSAEYCEQYVSYFCKMSRLLNTPDGSPYTWWVGKANEKHYYWGGSEPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLIPRGVFLENLGNTDFIKLELKSSTEVSFSFDVGNGPVEIVVRSPSPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLGCIRSLRMNGVTLDLEERAKVTSGFKSGCSGHCTSYGANCENGGKCIEKYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQALTVTARDTGSRAENSADQQQHLAPDLAQEQIHFSFSTTKAPCILLYVSSLTTDFLAVLVKPTGNLQIRYNLGGTREPFNIDVDHRNMANGQPHSVNITRHEKTIILKLDHYPAAGYHLPSSSDTIFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQFNHIAPLKAALRQTNASAHVHIQGDLVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEWLI

Keywords

Genome annotation databases

Similar Proteins

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