A0A8I6GD20 · A0A8I6GD20_RAT
- Proteinhistidine--tRNA ligase
- GeneZmat2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids496 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 121-123 | L-histidine (UniProtKB | ChEBI) | |||
Binding site | 148 | L-histidine (UniProtKB | ChEBI) | |||
Binding site | 164 | L-histidine (UniProtKB | ChEBI) | |||
Binding site | 168 | L-histidine (UniProtKB | ChEBI) | |||
Binding site | 317 | L-histidine (UniProtKB | ChEBI) | |||
Binding site | 321-322 | L-histidine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | mitochondrion | |
Cellular Component | nucleus | |
Cellular Component | U2-type precatalytic spliceosome | |
Cellular Component | U4/U6 x U5 tri-snRNP complex | |
Molecular Function | ATP binding | |
Molecular Function | histidine-tRNA ligase activity | |
Molecular Function | identical protein binding | |
Molecular Function | RNA binding | |
Biological Process | histidyl-tRNA aminoacylation | |
Biological Process | mRNA splicing, via spliceosome |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namehistidine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A8I6GD20
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 52-407 | Aminoacyl-transfer RNA synthetases class-II family profile | |||
Sequence similarities
Belongs to the class-II aminoacyl-tRNA synthetase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length496
- Mass (Da)56,112
- Last updated2022-05-25 v1
- Checksum9EFDF04B22BE3F6F
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
D4AD01 | D4AD01_RAT | Zmat2 | 199 | ||
A0A8I6AB48 | A0A8I6AB48_RAT | Zmat2 | 681 | ||
A0A8I6A401 | A0A8I6A401_RAT | Zmat2 | 513 | ||
A0A8I5ZM00 | A0A8I5ZM00_RAT | Hars2 | 467 | ||
F1M9C9 | F1M9C9_RAT | Hars2 | 507 |
Keywords
- Technical term