A0A8I6AVL3 · A0A8I6AVL3_RAT

  • Protein
    DNA (cytosine-5-)-methyltransferase
  • Gene
    Dnmt3b
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

Features

Showing features for active site.

1839100200300400500600700800
TypeIDPosition(s)Description
Active site637

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcatalytic complex
Cellular Componentchromosome, centromeric region
Cellular Componentheterochromatin
Cellular Componentnucleus
Molecular Functionchromatin binding
Molecular FunctionDNA (cytosine-5-)-methyltransferase activity
Molecular FunctionDNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
Molecular FunctionDNA binding
Molecular FunctionlncRNA binding
Molecular Functionmetal ion binding
Molecular Functionmethyltransferase activity
Molecular Functiontranscription corepressor activity
Biological Processautosome genomic imprinting
Biological Processcellular response to amino acid stimulus
Biological Processcellular response to dexamethasone stimulus
Biological Processcellular response to hyperoxia
Biological ProcessDNA methylation-dependent heterochromatin formation
Biological Processepigenetic programming of gene expression
Biological Processgene silencing by piRNA-directed DNA methylation
Biological Processheterochromatin formation
Biological Processmethylation
Biological Processnegative regulation of gene expression, epigenetic
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processpositive regulation of gene expression
Biological Processprotein-containing complex localization
Biological Processresponse to activity
Biological Processresponse to alcohol
Biological Processresponse to caffeine
Biological Processresponse to cocaine
Biological Processresponse to estradiol
Biological Processresponse to hypoxia
Biological Processresponse to ionizing radiation
Biological Processresponse to toxic substance
Biological Processresponse to vitamin A
Biological Processresponse to xenobiotic stimulus
Biological Processretrotransposon silencing by heterochromatin formation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA (cytosine-5-)-methyltransferase
  • EC number

Gene names

    • Name
      Dnmt3b

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I6AVL3

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    839
  • Mass (Da)
    94,574
  • Last updated
    2022-05-25 v1
  • Checksum
    3AA121E5D2D5A1D4
MKGDSRHLNEEEGASGYEDCIIVNGNCSDQSSDTKDAPSPPVLEAICTEPVCTPETRGRRSSSRLSKREVSSLLNYTQDVVGDGDGEADDGDGSDILMMPKLTRETKDARTPSESPAVRTRNSNSISSLERQRTSPRITRGRQGRYHVQEYPVEFPATKSRRRRASSSASTPWSSPASIELMEDVTPKSSSTPSVDLSQDGPQEGMDATQVDAESRDGDSTEYQDDKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMPGMRWVQWFGDGKFSEIAADKLVALGLFSQHFNLATFNKLVSYRKAMYHTLEKAMVRAGKTFPSRPGDSLEDQLKPMLEWAHGGFKPTGIEGLKPNNKQPENKSRRRTTIDFAASEYSTPPKRLKTNSYGGKDRGEDEESRERMASDVTNNKGNLEDRCLSCGKKNPVSFHPLFEGGLCQSCRDRFLELFYMYDEDGYQSYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGTGTAEDAKLQEPWSCYMCLPQRCHGVLRRRKDWNMRLQDFFTTDPDLEEFEPPKLYPAIPAAKRRPIRVLSLFDGIATGYLVLKDLGIKVEKYVASEVCAESIAVGTIKHEGQIKYVNDVRKITKKNIEEWGPFDLVIGGSPCNDLSNVNPARKGLYEGTGRLFFEFYHLLNYTRPKEGDNRPFFWMFENVVAMKVNDKKDISRFLACNPVMIDAIKVSAAHRARYFWGNLPGMNRPVIASKNDKLELQDCLEFSRTAKLKKVQTITTKSNSIRQGKNQLFPVVMNGKDDVLWCTELERIFGFPAHYTDVSNMGRGARQKLLGRSWSVPVIRHLFAPLKDYFACE

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8J8XG14A0A8J8XG14_RATDnmt3b860
A0A0G2JYR2A0A0G2JYR2_RATDnmt3b796

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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