A0A8I6ANH8 · A0A8I6ANH8_RAT

  • Protein
    Dedicator of cytokinesis 6
  • Gene
    Dock6
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    1/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionguanyl-nucleotide exchange factor activity
Biological Processsmall GTPase-mediated signal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Dedicator of cytokinesis 6

Gene names

    • Name
      Dock6

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I6ANH8

Proteomes

Organism-specific databases

Subcellular Location

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region23-44Disordered
Region155-190Disordered
Compositional bias160-177Basic and acidic residues
Region408-442Disordered
Compositional bias413-437Basic and acidic residues
Domain548-714C2 DOCK-type
Region1134-1154Disordered
Compositional bias1137-1154Polar residues
Domain1657-2093DOCKER

Sequence similarities

Belongs to the DOCK family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,117
  • Mass (Da)
    236,257
  • Last updated
    2022-05-25 v1
  • Checksum
    F59BB5AF660CE0FE
ILSFLVSHTPSCLPRTVAAEVRKQVSRERSGSPHSSRRSSSSLGVPLTEVIEPLDFEDVLLSRPPEVEPGPLRDMIEFPADDLELLKQPRECRTTESGVPEDGKLDAQVRAAVEMYSEDWVIVRRRYQHLSTAYSPITTETQRERQKGLTCQVFEQDTPGDERTGPEDVDDSQHCSGSPEDTPRSSGASGVFSLRNLAADSLLPTLLERAAPEDVDRRNEALRRQHRAPALLTLYPAPDEDEAVERCSHPEPPREHFGQRILVKCLSLKFEIEIEPIFGTLALYDVREKKKISENFYFDLNSDSVKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVVKLEKVLQQGDISECCEPYMVMKEADTVKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSVGPQDRDSDSEGERRPTWAERRRRGPQDRSYSGDDACSFSSFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKIDISPAPENLHFCLSPELLHVKPYPDPRGRPTKEILEFPAREVYAPHTCYRNLLFVYPHSLNFSSRQGSVRNLAVRIQYMAGEDQSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLRLPACVTENHHLFFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPHLDKFFTLVHVLEEGIFPFRLKETVLSEGTMEQELRASLAALRLASPEPLVAFSHHVLDKLVRLVVRPPVICGQMVNLGRGAFEAMAHVASLVHRNLEAVQDSRGHCPLLAAYVHYAFRLPGGDLGLPGEVPPATVQAATLARGSGRPASLYLARSKSISSSNPDLAVVPGSVDDEVSRILASKGVDRSHSWVNSAYAPGGSKAVLRRVPPYCGADPRQAIDRNSSRASSYLEASSSALPAPQLRHTVQKLLHEELALQWVVSGSAVRELVLQHAWFFFQLMVKSMELHLLLGQRLDTPRKLRFPGRFLDDIAALVASVGLEVITRVHKDMELAERLNASLAFFLSDLLSIADRGYIFSLVRAHYKQVATRLQSAPNPAALLTLRMDFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVISMFELSGPFRQQHFLSGLLLTELALALDPEAEGASLLHKKAITAVHNLLCSHDVDSRYTDATVKAKVAELYLPLLSLARDTLPRLHGFAEGSGQRSRLASMLDSDTEGEGDIGGTINPSVAMAIAGGPLAPGSRTSISQGPSTAARSGCPLSAESSRTLLVCVLWVLKNAEPALLQRWAADLALPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQEMVRRSRELLPPGTAEGGRAFPCVTGSDSSDITGSPLPSRTKDEVEHEALVDGNLATEASLVVLDMLEIIVQTVMLSEARESILGAVLKVVLYSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEIGHNFARVKMLVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDLGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLMDLMYRIARGYQGSPDLRLTWLQNMASKHAELGNHAEAAQCMVHAAALVAEYLALLEDSRHLPVGCVSFQNVSSNVLEESAISDDILSPDEEGFCSGKNFTDLGLVGLLEQAAAYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQVGLAQRVFGTYFRVGFYGARFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKLKLDPQKAYIQITYVEPHFDTYELKDRVTYFDRNYGLRAFLFCTPFTPDGRAHGELAEQHKRKTLLSTEHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLSEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERHYSRLREALQPLLTQRLPQLLAPSSTSLRNSINRSSFRKTDL

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
D3ZY19D3ZY19_RATDock62113
A0A0G2KAH4A0A0G2KAH4_RATDock62082
A0A8I5ZNP4A0A8I5ZNP4_RATDock61817

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias160-177Basic and acidic residues
Compositional bias413-437Basic and acidic residues
Compositional bias1137-1154Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp