A0A8I6ANH8 · A0A8I6ANH8_RAT
- ProteinDedicator of cytokinesis 6
- GeneDock6
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2117 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | guanyl-nucleotide exchange factor activity | |
Biological Process | small GTPase-mediated signal transduction |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A8I6ANH8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 23-44 | Disordered | ||||
Sequence: KQVSRERSGSPHSSRRSSSSLG | ||||||
Region | 155-190 | Disordered | ||||
Sequence: EQDTPGDERTGPEDVDDSQHCSGSPEDTPRSSGASG | ||||||
Compositional bias | 160-177 | Basic and acidic residues | ||||
Sequence: GDERTGPEDVDDSQHCSG | ||||||
Region | 408-442 | Disordered | ||||
Sequence: VGPQDRDSDSEGERRPTWAERRRRGPQDRSYSGDD | ||||||
Compositional bias | 413-437 | Basic and acidic residues | ||||
Sequence: RDSDSEGERRPTWAERRRRGPQDRS | ||||||
Domain | 548-714 | C2 DOCK-type | ||||
Sequence: RNLLFVYPHSLNFSSRQGSVRNLAVRIQYMAGEDQSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLRLPACVTENHHLFFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAV | ||||||
Region | 1134-1154 | Disordered | ||||
Sequence: ASPSPSVSSTTSQSSTFSSQA | ||||||
Compositional bias | 1137-1154 | Polar residues | ||||
Sequence: SPSVSSTTSQSSTFSSQA | ||||||
Domain | 1657-2093 | DOCKER | ||||
Sequence: RGYQGSPDLRLTWLQNMASKHAELGNHAEAAQCMVHAAALVAEYLALLEDSRHLPVGCVSFQNVSSNVLEESAISDDILSPDEEGFCSGKNFTDLGLVGLLEQAAAYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQVGLAQRVFGTYFRVGFYGARFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKLKLDPQKAYIQITYVEPHFDTYELKDRVTYFDRNYGLRAFLFCTPFTPDGRAHGELAEQHKRKTLLSTEHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLSEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERHYSRLREALQPLLTQRLP |
Sequence similarities
Belongs to the DOCK family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,117
- Mass (Da)236,257
- Last updated2022-05-25 v1
- ChecksumF59BB5AF660CE0FE
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
D3ZY19 | D3ZY19_RAT | Dock6 | 2113 | ||
A0A0G2KAH4 | A0A0G2KAH4_RAT | Dock6 | 2082 | ||
A0A8I5ZNP4 | A0A8I5ZNP4_RAT | Dock6 | 1817 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 160-177 | Basic and acidic residues | ||||
Sequence: GDERTGPEDVDDSQHCSG | ||||||
Compositional bias | 413-437 | Basic and acidic residues | ||||
Sequence: RDSDSEGERRPTWAERRRRGPQDRS | ||||||
Compositional bias | 1137-1154 | Polar residues | ||||
Sequence: SPSVSSTTSQSSTFSSQA |
Keywords
- Technical term