A0A8I6A8K2 · A0A8I6A8K2_RAT

  • Protein
    Glycine receptor, alpha 1
  • Gene
    Glra1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site, site.

147050100150200250300350400450
Type
IDPosition(s)Description
Binding site242-247strychnine (UniProtKB | ChEBI)
Site301Important for obstruction of the ion pore in the closed conformation

GO annotations

AspectTerm
Cellular Componentchloride channel complex
Cellular Componentdendrite
Cellular Componentexternal side of plasma membrane
Cellular Componentglycinergic synapse
Cellular Componentinhibitory synapse
Cellular Componentintracellular membrane-bounded organelle
Cellular Componentperikaryon
Cellular Componentpostsynaptic membrane
Molecular Functionextracellularly glycine-gated chloride channel activity
Molecular Functionglycine binding
Molecular Functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
Molecular Functiontaurine binding
Molecular Functiontransmembrane signaling receptor activity
Molecular Functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
Molecular Functionzinc ion binding
Biological Processacrosome reaction
Biological Processadult walking behavior
Biological Processcellular response to amino acid stimulus
Biological Processcellular response to ethanol
Biological Processcellular response to zinc ion
Biological Processinhibitory postsynaptic potential
Biological Processmuscle contraction
Biological Processnegative regulation of transmission of nerve impulse
Biological Processneuromuscular process controlling posture
Biological Processneuronal action potential
Biological Processneuropeptide signaling pathway
Biological Processpositive regulation of acrosome reaction
Biological Processregulation of respiratory gaseous exchange by nervous system process
Biological Processrighting reflex
Biological Processstartle response
Biological Processsynaptic transmission, glycinergic
Biological Processvisual perception

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Glycine receptor, alpha 1

Gene names

    • Name
      Glra1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I6A8K2

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane262-284Helical
Transmembrane325-348Helical
Transmembrane442-462Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond178↔192
Disulfide bond238↔249

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain55-260Neurotransmitter-gated ion-channel ligand-binding
Domain267-374Neurotransmitter-gated ion-channel transmembrane

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    470
  • Mass (Da)
    53,730
  • Last updated
    2022-05-25 v1
  • MD5 Checksum
    7B0D2881D6A0CC5F93336828B5107441
IWTSQKVISYSLSYVAEQGCASSTLCFSLLSLAASKEADAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKSEAFFFPWFFLFDDEGGEGRFNFSAYGMGPACLQAKDGISVKGANNNNTTNPAPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNK

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P07727GLRA1_RATGlra1457
Q99JD0Q99JD0_RATGlra161
A0A8I6GGT5A0A8I6GGT5_RATGlra1445

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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