A0A8I6A8K2 · A0A8I6A8K2_RAT
- ProteinGlycine receptor, alpha 1
- GeneGlra1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids470 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- chloride(in) = chloride(out)
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 242-247 | strychnine (UniProtKB | ChEBI) | |||
Site | 301 | Important for obstruction of the ion pore in the closed conformation | |||
GO annotations
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A8I6A8K2
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Postsynaptic cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 262-284 | Helical | |||
Transmembrane | 325-348 | Helical | |||
Transmembrane | 442-462 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 178↔192 | ||||
Disulfide bond | 238↔249 | ||||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 55-260 | Neurotransmitter-gated ion-channel ligand-binding | |||
Domain | 267-374 | Neurotransmitter-gated ion-channel transmembrane | |||
Sequence similarities
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length470
- Mass (Da)53,730
- Last updated2022-05-25 v1
- MD5 Checksum7B0D2881D6A0CC5F93336828B5107441
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P07727 | GLRA1_RAT | Glra1 | 457 | ||
Q99JD0 | Q99JD0_RAT | Glra1 | 61 | ||
A0A8I6GGT5 | A0A8I6GGT5_RAT | Glra1 | 445 |
Keywords
- Technical term