A0A8I6A623 · A0A8I6A623_RAT

  • Protein
    non-specific serine/threonine protein kinase
  • Gene
    Mark4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    4/5

Function

Catalytic activity

Features

Showing features for binding site.

168850100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site88ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcentrosome
Cellular Componentciliary basal body
Cellular Componentcytoplasm
Cellular Componentdendrite
Cellular Componentgamma-tubulin complex
Cellular Componentmicrotubule cytoskeleton
Cellular Componentmicrotubule organizing center
Cellular Componentmidbody
Cellular Componentneuron projection
Molecular FunctionATP binding
Molecular Functioncytoskeletal anchor activity
Molecular Functiongamma-tubulin binding
Molecular Functionmicrotubule binding
Molecular Functionprotein serine/threonine kinase activity
Molecular Functiontau-protein kinase activity
Biological Processcilium organization
Biological Processintracellular signal transduction
Biological Processmicrotubule bundle formation
Biological Processmicrotubule cytoskeleton organization
Biological Processnervous system development
Biological Processpositive regulation of cell cycle
Biological Processpositive regulation of cilium assembly
Biological Processpositive regulation of NLRP3 inflammasome complex assembly
Biological Processpositive regulation of protein localization to centrosome
Biological Processprotein phosphorylation
Biological Processregulation of centrosome cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • Name
      Mark4

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I6A623

Proteomes

Organism-specific databases

Structure

3D structure databases

Family & Domains

Features

Showing features for region, domain, compositional bias.

Type
IDPosition(s)Description
Region1-36Disordered
Domain59-310Protein kinase
Domain324-368UBA
Region385-614Disordered
Compositional bias390-413Polar residues
Compositional bias441-455Basic and acidic residues
Compositional bias465-480Polar residues
Compositional bias494-552Polar residues
Region628-661Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    688
  • Mass (Da)
    75,400
  • Last updated
    2022-05-25 v1
  • Checksum
    88C064C320D8D2EE
MSSRTALAPGNDRNSDTHGTLGSGRSSDKGPSWSSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKEALTNQKYNEVTATYLLLGRKTEEGGDRGAPGLALARVRAPSDTTNGTSSSKGSSHNKGQRTSSSTYHRQRRHSDFCGPSPAPLHPKRSPTSTGDTELKEERLPGRKASCSAAGSGSRGLPPSSPMVSSAHNPNKAEIPERRKDSTSTPNNLPPSMMTRRNTYVCTERPGSERQSLLPNGKENSSGTSRVPPASPSSHSLAPPSGERSRLARGSTIRSTFHGGQVRDRRAGGGSGGGVQNGPPASPTLAHEAAPLPSGRPRPTTNLFTKLTSKLTRRVTLDPSKRQNSNRCVSGASLPQGSKIRSQTNLRESGDLRSQVAIYLGIKRKPPPGCSDSPGV

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
D4A6T9D4A6T9_RATMark4752
A0A0G2JTD8A0A0G2JTD8_RATMark4744

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias390-413Polar residues
Compositional bias441-455Basic and acidic residues
Compositional bias465-480Polar residues
Compositional bias494-552Polar residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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