Genome sequence of the Brown Norway rat yields insights into mammalian evolution.Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C.[...], Collins F.S.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainBrown NorwayCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCNature 428:493-521 (2004)Cited in99+99+
No title available.EnsemblCited forIDENTIFICATIONStrainBrown NorwaySourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Expression of mitogen-activated protein kinase pathways during postnatal development of rat heart.Kim S.O., Irwin P., Katz S., Pelech S.L.View abstractCategoriesSubcellular LocationSourceRGD: 70500PubMedEurope PMCJ Cell Biochem 71:286-301 (1998)Mapped to36
Immunolocalization of the mitogen-activated protein kinases p42MAPK and JNK1, and their regulatory kinases MEK1 and MEK4, in adult rat central nervous system.Flood D.G., Finn J.P., Walton K.M., Dionne C.A., Contreras P.C., Miller M.S., Bhat R.V.View abstractCategoriesSubcellular LocationSourceRGD: 70500PubMedEurope PMCJ Comp Neurol 398:373-392 (1998)Mapped to16
ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation.Gille H., Kortenjann M., Thomae O., Moomaw C., Slaughter C., Cobb M.H., Shaw P.E.View abstractCategoriesFunction, Subcellular LocationSourceRGD: 70500, RGD: 70500PubMedEurope PMCEMBO J. 14:951-962 (1995)Cited in1Mapped to32
Phosphorylation of tristetraprolin, a potential zinc finger transcription factor, by mitogen stimulation in intact cells and by mitogen-activated protein kinase in vitro.Taylor G.A., Thompson M.J., Lai W.S., Blackshear P.J.View abstractCategoriesFunctionSourceRGD: 70500PubMedEurope PMCJ. Biol. Chem. 270:13341-13347 (1995)Cited in1Mapped to5
ERK2-type mitogen-activated protein kinase (MAPK) and its substrates in postsynaptic density fractions from the rat brain.Suzuki T., Okumura-Noji K., Nishida E.View abstractCategoriesSubcellular LocationSourceRGD: 70500PubMedEurope PMCNeurosci Res 22:277-285 (1995)Mapped to8
7,8-Dihydroxycoumarin exerts antitumor potential on DMBA-induced mammary carcinogenesis by inhibiting ERalpha, PR, EGFR, and IGF1R: involvement of MAPK1/2-JNK1/2-Akt pathway.Kumar A., Sunita P., Jha S., Pattanayak S.P.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCJ Physiol Biochem 74:223-234 (2018)Mapped to4
Protection by mTOR Inhibition on Zymosan-Induced Systemic Inflammatory Response and Oxidative/Nitrosative Stress: Contribution of mTOR/MEK1/ERK1/2/IKKbeta/IkappaB-alpha/NF-kappaB Signalling Pathway.Sahan-Firat S., Temiz-Resitoglu M., Guden D.S., Kucukkavruk S.P., Tunctan B., Sari A.N., Kocak Z., Malik K.U.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCInflammation 41:276-298 (2018)Mapped to4
Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging.Isensee J., Schild C., Schwede F., Hucho T.View abstractCategoriesFunctionSourceRGD: 70500PubMedEurope PMCJ Cell Sci 130:2134-2146 (2017)Mapped to4
Brd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-beta-mediated Nox4 expression.Zhou B., Mu J., Gong Y., Lu C., Zhao Y., He T., Qin Z.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCRedox Biol 11:390-402 (2017)Mapped to37
Paridis Rhizoma Sapoinins attenuates liver fibrosis in rats by regulating the expression of RASAL1/ERK1/2 signal pathway.Hong Y., Han Y.Q., Wang Y.Z., Gao J.R., Li Y.X., Liu Q., Xia L.Z.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCJ Ethnopharmacol 192:114-122 (2016)Mapped to5
The Impact of Small RNA Interference Against Homer1 on Rats with Type 2 Diabetes and ERK Phosphorylation.Lu J., Gan J., Fu G., Ding L., Zheng Q.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCCell Biochem Biophys 73:597-601 (2015)Mapped to4
Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7beta-Aurora A pathway.Duhamel S., Girondel C., Dorn J.F., Tanguay P.L., Voisin L., Smits R., Maddox P.S., Meloche S.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCCell Cycle 15:1631-1642 (2016)Mapped to43
Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis.Kim H., Banerjee N., Ivanov I., Pfent C.M., Prudhomme K.R., Bisson W.H., Dashwood R.H., Talcott S.T., Mertens-Talcott S.U.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCMol Nutr Food Res 60:1912-1923 (2016)Mapped to2
Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding.McReynolds A.C., Karra A.S., Li Y., Lopez E.D., Turjanski A.G., Dioum E., Lorenz K., Zaganjor E., Stippec S.[...], Cobb M.H.View abstractCategoriesFunctionSourceRGD: 70500PubMedEurope PMCBiochemistry 55:1909-1917 (2016)Mapped to2
MAPK1 up-regulates the expression of MALAT1 to promote the proliferation of cardiomyocytes through PI3K/AKT signaling pathway.Zhao J., Li L., Peng L.View abstractCategoriesFunctionSourceRGD: 70500PubMedEurope PMCInt J Clin Exp Pathol 8:15947-15953 (2015)Mapped to3
[Effects of hydrogen sulfide on myocardial fibrosis and MAPK1/3 and MMP-8 expression in diabetic rats].Li F., Zeng O., Luo J., Wu Z.X., Xiao T., Zhang J.J., Yang J.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCNan Fang Yi Ke Da Xue Xue Bao 35:549-552 (2015)Mapped to4
[Effect of moxibustion intervention on expression of gastric epidermal growth factor receptor and extracellular signal regulated kinase 1/2 expression in rats with gastric ulcer].Zhang H., Guo H., Zhang Y.C., Liu M., Ai K., Su Y.M., Li M.H., Li T.L.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCZhen Ci Yan Jiu 39:351-357 (2014)Mapped to4
Sevoflurane post-conditioning protects isolated rat hearts against ischemia-reperfusion injury via activation of the ERK1/2 pathway.Xie H., Zhang J., Zhu J., Liu L.X., Rebecchi M., Hu S.M., Wang C.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCActa Pharmacol Sin 35:1504-1513 (2014)Mapped to5
MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by alpha1-adrenergic receptors.Ogata T., Naito D., Nakanishi N., Hayashi Y.K., Taniguchi T., Miyagawa K., Hamaoka T., Maruyama N., Matoba S.[...], Ueyama T.View abstractCategoriesInteraction, Subcellular LocationSourceRGD: 70500, RGD: 70500PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 111:3811-3816 (2014)Cited in11Mapped to2
The antifibrotic effect of a serine protease inhibitor in the kidney.Morinaga J., Kakizoe Y., Miyoshi T., Onoue T., Ueda M., Mizumoto T., Yamazoe R., Uchimura K., Hayata M.[...], Kitamura K.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCAm J Physiol Renal Physiol 305:F173-81 (2013)Mapped to2
Activation of VEGF and ERK1/2 and improvement of urethral function by adipose-derived stem cells in a rat stress urinary incontinence model.Li G.Y., Zhou F., Gong Y.Q., Cui W.S., Yuan Y.M., Song W.D., Xin H., Liu T., Li W.R.[...], Xin Z.C.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCUrology 80:953.e1-8 (2012)Mapped to2
Acute treatment with bone marrow-derived mononuclear cells attenuates the organ injury/dysfunction induced by hemorrhagic shock in the rat.Nandra K.K., Takahashi K., Collino M., Benetti E., Wong W.S., Goh F.Y., Suzuki K., Patel N.S., Thiemermann C.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCShock 37:592-598 (2012)Mapped to2
Curcumin attenuates diabetic nephropathy by inhibiting PKC-alpha and PKC- beta1 activity in streptozotocin-induced type I diabetic rats.Soetikno V., Watanabe K., Sari F.R., Harima M., Thandavarayan R.A., Veeraveedu P.T., Arozal W., Sukumaran V., Lakshmanan A.P.[...], Suzuki K.View abstractCategoriesPhenotypes & VariantsSourceRGD: 70500PubMedEurope PMCMol Nutr Food Res 55:1655-1665 (2011)Mapped to2