A0A8I6A1J3 · A0A8I6A1J3_RAT

  • Protein
    Dual specificity mitogen-activated protein kinase kinase 1
  • Gene
    Map2k1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site75ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcentrosome
Cellular Componentearly endosome
Cellular Componentfocal adhesion
Cellular Componentlate endosome
Cellular Componentmitochondrion
Cellular Componentnucleus
Cellular Componentspindle pole body
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processprotein phosphorylation
Biological Processregulation of early endosome to late endosome transport
Biological Processregulation of Golgi inheritance
Biological Processregulation of stress-activated MAPK cascade

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dual specificity mitogen-activated protein kinase kinase 1
  • EC number
  • Alternative names
    • ERK activator kinase 1
    • MAPK/ERK kinase 1

Gene names

    • Name
      Map2k1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I6A1J3

Proteomes

Organism-specific databases

PTM/Processing

Keywords

Family & Domains

Features

Showing features for coiled coil, domain.

Type
IDPosition(s)Description
Coiled coil1-28
Domain46-339Protein kinase

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    371
  • Mass (Da)
    41,405
  • Last updated
    2022-05-25 v1
  • Checksum
    96310D7C6B3DCD6A
MKLERTNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAASI

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q01986MP2K1_RATMap2k1393
A0A8I6AEA6A0A8I6AEA6_RATMap2k1358
A0A8I6A048A0A8I6A048_RATMap2k1369
A0A0H2UHI2A0A0H2UHI2_RATMap2k1390
A0A8I5ZT77A0A8I5ZT77_RATMap2k1368

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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