A0A8I6A0G0 · A0A8I6A0G0_RAT

  • Protein
    Serine/threonine-protein kinase receptor
  • Gene
    Bmpr1b
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site279ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentdendrite
Cellular Componentneuronal cell body
Cellular Componentplasma membrane
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular FunctionBMP binding
Molecular FunctionBMP receptor activity
Molecular Functionmetal ion binding
Molecular Functionprotein serine/threonine kinase activity
Molecular FunctionSMAD binding
Molecular Functiontransforming growth factor beta receptor activity, type I
Molecular Functiontransmembrane receptor protein serine/threonine kinase activity
Molecular Functiontransmembrane signaling receptor activity
Biological ProcessBMP signaling pathway
Biological Processbone development
Biological Processcamera-type eye development
Biological Processcartilage condensation
Biological Processcell differentiation
Biological Processcell surface receptor protein serine/threonine kinase signaling pathway
Biological Processcellular response to BMP stimulus
Biological Processcellular response to growth factor stimulus
Biological Processcentral nervous system neuron differentiation
Biological Processchondrocyte differentiation
Biological Processdorsal/ventral pattern formation
Biological Processeye development
Biological Processinflammatory response
Biological Processosteoblast differentiation
Biological Processovarian cumulus expansion
Biological Processovulation cycle
Biological Processpositive regulation of bone mineralization
Biological Processpositive regulation of extrinsic apoptotic signaling pathway via death domain receptors
Biological Processpositive regulation of gene expression
Biological Processpositive regulation of osteoblast differentiation
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processretina development in camera-type eye
Biological Processretinal ganglion cell axon guidance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein kinase receptor
  • EC number

Gene names

    • Name
      Bmpr1b

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I6A0G0

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane175-196Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain222-251GS
Domain252-542Protein kinase

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    550
  • Mass (Da)
    62,217
  • Last updated
    2022-05-25 v1
  • Checksum
    15BB2A6DEA8830D2
MCDLGAFITLRRRSSMAKNFPPPSPSSNCSGIFLLSLWDNSLEKFVDNMLLRSSGKLNVGTKKEDGESTAPTARPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGTPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKDRDFVDGPIHHKALLISVTVCSLLLVLIILFCYFRYKRQEARPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRTHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8I5ZJI2A0A8I5ZJI2_RATBmpr1b502
M0R3J4M0R3J4_RATBmpr1b491
A0A8I5ZXN2A0A8I5ZXN2_RATBmpr1b550

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp