A0A8I5ZYX7 · A0A8I5ZYX7_RAT

  • Protein
    Hairy/enhancer-of-split related with YRPW motif protein 1
  • Gene
    Hey1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleoplasm
Cellular Componentnucleus
Molecular Functioncis-regulatory region sequence-specific DNA binding
Molecular FunctionDNA-binding transcription factor activity
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular FunctionDNA-binding transcription repressor activity, RNA polymerase II-specific
Molecular Functionidentical protein binding
Molecular Functionprotein dimerization activity
Molecular FunctionRNA polymerase II-specific DNA-binding transcription factor binding
Molecular Functionsequence-specific DNA binding
Molecular Functionsequence-specific double-stranded DNA binding
Biological Processangiogenesis
Biological Processanterior/posterior axis specification
Biological Processaortic valve morphogenesis
Biological Processarterial endothelial cell differentiation
Biological Processartery development
Biological Processatrioventricular valve formation
Biological Processatrioventricular valve morphogenesis
Biological Processblood vessel development
Biological Processblood vessel endothelial cell differentiation
Biological Processcardiac epithelial to mesenchymal transition
Biological Processcardiac septum morphogenesis
Biological Processcardiac ventricle morphogenesis
Biological Processcellular response to glucocorticoid stimulus
Biological Processcomma-shaped body morphogenesis
Biological Processdorsal aorta morphogenesis
Biological Processendocardial cushion morphogenesis
Biological Processendocardial cushion to mesenchymal transition involved in heart valve formation
Biological Processepithelial to mesenchymal transition involved in endocardial cushion formation
Biological Processestablishment of epithelial cell polarity
Biological Processinner ear receptor cell stereocilium organization
Biological Processlabyrinthine layer blood vessel development
Biological Processmesenchymal cell development
Biological Processnegative regulation of biomineral tissue development
Biological Processnegative regulation of DNA-templated transcription
Biological Processnegative regulation of gene expression
Biological Processnegative regulation of neuron differentiation
Biological Processnegative regulation of Notch signaling pathway
Biological Processnegative regulation of smooth muscle cell differentiation
Biological Processnegative regulation of transcription by RNA polymerase II
Biological ProcessNotch signaling pathway
Biological Processosteoblast development
Biological Processoutflow tract morphogenesis
Biological Processpositive regulation of osteoblast differentiation
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processpulmonary valve morphogenesis
Biological Processregulation of epithelial cell proliferation
Biological Processregulation of inner ear auditory receptor cell differentiation
Biological Processregulation of vasculogenesis
Biological Processrenal vesicle development
Biological ProcessS-shaped body morphogenesis
Biological Processumbilical cord morphogenesis
Biological Processureteric bud morphogenesis
Biological Processvasculogenesis
Biological Processventricular septum morphogenesis
Biological Processventricular trabecula myocardium morphogenesis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Hairy/enhancer-of-split related with YRPW motif protein 1

Gene names

    • Name
      Hey1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I5ZYX7

Proteomes

Organism-specific databases

Subcellular Location

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-165Disordered
Compositional bias180-196Pro residues
Region180-221Disordered
Region240-270Disordered
Compositional bias246-261Pro residues
Region292-373Disordered
Compositional bias346-367Polar residues
Domain367-422BHLH
Domain444-476Orange
Region510-552Disordered
Compositional bias518-532Polar residues

Sequence similarities

Belongs to the HEY family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    617
  • Mass (Da)
    65,312
  • Last updated
    2022-05-25 v1
  • Checksum
    E466A4AC16AD521F
EALKDCHGLPEPKRQHPLIGAPGSAPRAGGHHPNERRLGRLFLQDPPTVRASRRWAPTAVPRAGRGQGLPGPAGARTPITGSHQEPGRRALAQPRSPARLFFSIHADAQSCRRRRQRGRRRRPSGLAGGRGAGTFPRPAARAAHRRRCRRGPGTRPGQSGRAGWGGSVAIAGLVSPAGPPFLPAAGPPPPAAPSRAPAEPTHCRRAGAGSRGGAQRAWSARPAPLRLPIRVARRRLAGARGCPGAAAPPLPQPPRLLRPPPIPGKGRSVGKGWLSFNQRLSVSGISVHAPPAAERRAAAQLTPPCPPRDPPGSPRSATMKRAHPDYSSSDSELDETIEVEKESADENGNLSSALGSMSPTTSSQVLARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAASGAHGGLGHIPWGSAFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLASAHPEAPALRAPPSGGLGPVLPVVTSASKLSPPLLSSVASLSAFPFSFSSFHLLSPSTPSQAANLGKPYRPWGTEIGAF

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias180-196Pro residues
Compositional bias246-261Pro residues
Compositional bias346-367Polar residues
Compositional bias518-532Polar residues

Keywords

Genome annotation databases

Similar Proteins

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