A0A8I5ZYW7 · A0A8I5ZYW7_RAT

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcentrosome
Cellular Componentcytoplasm
Cellular Componentnucleus
Cellular ComponentPML body
Cellular Componentprotein-containing complex
Cellular Componenttranscription regulator complex
Cellular Componenttranscription repressor complex
Molecular Functionchromatin binding
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular FunctionDNA-binding transcription factor binding
Molecular FunctionDNA-binding transcription repressor activity, RNA polymerase II-specific
Molecular Functionhistone deacetylase inhibitor activity
Molecular Functionidentical protein binding
Molecular Functionprotein domain specific binding
Molecular Functionprotein kinase binding
Molecular FunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular FunctionSMAD binding
Molecular Functionubiquitin protein ligase binding
Molecular Functionzinc ion binding
Biological Processanterior/posterior axis specification
Biological Processbone morphogenesis
Biological Processcamera-type eye development
Biological Processcamera-type eye morphogenesis
Biological Processcardiac muscle cell proliferation
Biological Processembryonic limb morphogenesis
Biological Processface morphogenesis
Biological Processfibroblast proliferation
Biological Processlens morphogenesis in camera-type eye
Biological Processmyelination in peripheral nervous system
Biological Processmyotube differentiation
Biological Processnegative regulation of activin receptor signaling pathway
Biological Processnegative regulation of BMP signaling pathway
Biological Processnegative regulation of cell population proliferation
Biological Processnegative regulation of fibroblast proliferation
Biological Processnegative regulation of osteoblast differentiation
Biological Processnegative regulation of Schwann cell proliferation
Biological Processnegative regulation of SMAD protein signal transduction
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processnegative regulation of transforming growth factor beta receptor signaling pathway
Biological Processneural tube closure
Biological Processnose morphogenesis
Biological Processolfactory bulb development
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processretina development in camera-type eye
Biological Processroof of mouth development
Biological Processskeletal muscle fiber development
Biological Processsomatic stem cell population maintenance

Names & Taxonomy

Protein names

  • Recommended name
    Ski oncogene
  • Alternative names
    • Proto-oncogene c-Ski

Gene names

    • Name
      Ski

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I5ZYW7

Proteomes

Organism-specific databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain217-312c-SKI SMAD4-binding
Region431-493Disordered
Compositional bias449-472Polar residues
Region662-686Disordered

Sequence similarities

Belongs to the SKI family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    686
  • Mass (Da)
    75,959
  • Last updated
    2022-05-25 v1
  • Checksum
    CB3144418446F1FD
MEAAAAGRGGFQPHPGLQKTLEQFHLSSMSSLGGPAAFSARWAQEAYKKESAKEAGAATVPAPVPTAAEPPPVLHLPAIQPPPPVLPGPFFMPSDRSTERCETVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKFDYANKYKRRVPRSLGCAHPRQRLSAFRPWSPAVSASEKETSPHLPALIRDSFYSYKSFETAVAPNVALAPPTQQKVVNSPPCTTVVSRAPEPLTTCIQPRKRKLTMDAPGAPDMLTPVAAAEEDKDSEAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLSSPGMHAPPVAAPDAAAHADAPSGLEAELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEKLTAALQAKRSLHQELEFLRVAKKEKLREATEAKRSLRKEIERLRAENEKKMKEANESRVRLKRELEQARQVRVCDKGCEAGRLRAKYSAQIEDLQAKLQHAEADREQLRADLLREREAREHLEKVVKELQEQLWPRPRPENSGGESNAELDP

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0G2K628A0A0G2K628_RATSki727

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias449-472Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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