A0A8I5ZY41 · A0A8I5ZY41_RAT
- ProteinPhosphodiesterase
- GenePde4b
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids736 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- 3',5'-cyclic AMP + H2O = AMP + H+This reaction proceeds in the forward direction.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.
Pathway
Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
GO annotations
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphodiesterase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A8I5ZY41
Proteomes
Organism-specific databases
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length736
- Mass (Da)83,349
- Last updated2022-05-25 v1
- MD5 Checksum31C884F66D42A3CF360A1CF10C754940
Computationally mapped potential isoform sequences
There are 6 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P14646 | PDE4B_RAT | Pde4b | 736 | ||
F1M1T9 | F1M1T9_RAT | Pde4b | 656 | ||
A0A8I6AT13 | A0A8I6AT13_RAT | Pde4b | 721 | ||
A0A8L2Q3F0 | A0A8L2Q3F0_RAT | Pde4b | 503 | ||
D3ZLB2 | D3ZLB2_RAT | Pde4b | 659 | ||
A0A8I5ZX49 | A0A8I5ZX49_RAT | Pde4b | 212 |
Keywords
- Technical term