A0A8I5ZWJ2 · A0A8I5ZWJ2_RAT

Function

Catalytic activity

Features

Showing features for binding site, active site.

1781100200300400500600700
TypeIDPosition(s)Description
Binding site567-575ATP (UniProtKB | ChEBI)
Binding site590ATP (UniProtKB | ChEBI)
Active site683Proton acceptor

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytoplasmic side of plasma membrane
Cellular Componentcytoplasmic vesicle
Cellular Componentfocal adhesion
Cellular Componentmicrotubule cytoskeleton
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functionimmunoglobulin receptor binding
Molecular Functionmicrotubule binding
Molecular Functionnon-membrane spanning protein tyrosine kinase activity
Molecular Functionphosphatidylinositol binding
Molecular Functionprotein kinase activity
Molecular Functionprotein tyrosine kinase activity
Biological Processcardiac muscle cell proliferation
Biological Processcell adhesion
Biological Processcellular response to vitamin D
Biological Processcentrosome cycle
Biological Processchemotaxis
Biological Processmicrotubule bundle formation
Biological Processmyoblast proliferation
Biological Processpeptidyl-tyrosine phosphorylation
Biological Processpositive regulation of microtubule polymerization
Biological Processpositive regulation of monocyte differentiation
Biological Processpositive regulation of myeloid cell differentiation
Biological Processpositive regulation of neuron projection development
Biological Processregulation of cell adhesion
Biological Processregulation of cell differentiation
Biological Processregulation of cell motility
Biological Processregulation of cell population proliferation
Biological Processregulation of cell shape
Biological Processregulation of mast cell degranulation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine-protein kinase
  • EC number

Gene names

    • Name
      Fes

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I5ZWJ2

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain, coiled coil, region.

TypeIDPosition(s)Description
Domain1-260F-BAR
Coiled coil135-162
Region392-421Disordered
Domain460-549SH2
Domain561-781Protein kinase

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    781
  • Mass (Da)
    88,604
  • Last updated
    2022-05-25 v1
  • Checksum
    32B2F44D2C7FFED9
MGFSSELCSPQGHGAVQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMSLQDSGGQSWSSGPDSPVSQSWAEITSQTENLSRVLRQHAEDLNSGPLSKLSVLIRERQHLRKTYNEQWQQLQQELTKTHSQDIEKLKSQYRTLTRDSAQARRKYQEASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRAAQLHHQHYHQFMLPGLLQSLQDLHEEMAGILKDILQEYLEISSLVQDDVASIHRELAAAAARIQPEFEYLGFLRQYGSAPDVPPCVTFDVSLLEEGEQLEPGDLQLNELTLESVQHTLTSVTDELAVATKEVLSRQEMVSQLQRELQCEEQNTHPRERVQLLGKRQVLQEAMQGLQVALCNQDKLQAQQELLQSKMEQLGTGEPPAVPLLQDDRHSTSSTEQERDGGRTPTLEIIKSHFSGIFRPKFSIPPPLQLVPEVQKPLHEQLWYHGAIPRAEVAELLTHSGDFLVRESQGKQEYVLSVLWDGQPRHFIIQSSDNLYRLEGDGFPSIPLLITHLLSSQQPLTKKSGVVLFRAVPKDKWVLKHEDLVLGEQIGRGNFGEVFSGRLRADNTPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGIYAASAGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLTNQQTREFVEKGKATDL

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
D4A584D4A584_RATFes822

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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