Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0A8I5ZTS2 · A0A8I5ZTS2_RAT

  • Protein
    RT1 class Ib, locus M3, gene 1
  • Gene
    RT1-M3-1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcis-Golgi network membrane
Cellular Componentearly endosome
Cellular Componentexternal side of plasma membrane
Cellular Componentextracellular space
Cellular ComponentMHC class Ib protein complex
Cellular Componentplasma membrane
Molecular FunctionCD8 receptor binding
Molecular Functionidentical protein binding
Molecular Functionpeptide antigen binding
Molecular Functionprotein homodimerization activity
Molecular Functionsignaling receptor binding
Biological Processalpha-beta T cell activation involved in immune response
Biological Processantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
Biological Processantigen processing and presentation of endogenous peptide antigen via MHC class Ib
Biological Processantigen processing and presentation of exogenous peptide antigen via MHC class Ib
Biological Processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
Biological Processdefense response to bacterium
Biological Processimmune response
Biological Processimmune response-inhibiting cell surface receptor signaling pathway
Biological Processnegative regulation of angiogenesis
Biological Processnegative regulation of dendritic cell differentiation
Biological Processnegative regulation of G0 to G1 transition
Biological Processnegative regulation of natural killer cell mediated cytotoxicity
Biological Processnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Processnegative regulation of T cell mediated cytotoxicity
Biological Processnegative regulation of T cell proliferation
Biological Processnitric oxide biosynthetic process
Biological Processperipheral B cell tolerance induction
Biological Processpositive regulation of cellular senescence
Biological Processpositive regulation of endothelial cell apoptotic process
Biological Processpositive regulation of interleukin-12 production
Biological Processpositive regulation of macrophage cytokine production
Biological Processpositive regulation of natural killer cell cytokine production
Biological Processpositive regulation of natural killer cell mediated cytotoxicity
Biological Processpositive regulation of nitric oxide biosynthetic process
Biological Processpositive regulation of regulatory T cell differentiation
Biological Processpositive regulation of T cell mediated cytotoxicity
Biological Processpositive regulation of T cell tolerance induction
Biological Processpositive regulation of tolerance induction
Biological Processpositive regulation of type II interferon production
Biological Processprotection from natural killer cell mediated cytotoxicity
Biological Processprotein homotrimerization
Biological Processresponse to molecule of bacterial origin

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • RT1 class Ib, locus M3, gene 1

Gene names

    • Name
      RT1-M3-1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A8I5ZTS2

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane305-331Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-24
ChainPRO_503519691225-393

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain209-297Ig-like

Sequence similarities

Belongs to the MHC class I family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    393
  • Mass (Da)
    44,644
  • Last updated
    2022-05-25 v1
  • MD5 Checksum
    1072918E81C3F75C143F8473A14312B9
MATSNKFSLLLMVVVALAVSRTGAGTHSLRYFHTALSRPGRGEPQYISVGYVDDKLFQRCDSVEEIPRMEARAPWMEKEGPEYWEELKLKVKSIAQRARARLRTLIRYYNQSEGSSHILQWMVACEVGPDMRLLGAHYQAAYDGSDYITLNEDLSSWTAADMVAQITKSELESEGRAEYFRAYVDGECLELLHRFLQNGKEILQRADPPKAHVTLHPRPEGDVTLRCWALGFYPADITLTWQLNGEDLTQDMELVETKPSGDGTFQKWASVVVPSGEEQKYTCHVEHEGLPEPLVLKWGGSSQSFVVIMVIIVIIVILALLGGVLTVVLVYRRRGAGKQKGSLSYLPHLWTSGLRWNWPCLFCRKTFDPPPQMTQWFILLNHCILLCIYECMI

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
G3V627G3V627_RATRT1-M3-1339
Q6MFW8Q6MFW8_RATRT1-M3-1339
M0R866M0R866_RATRT1-M3-1352
A0A8I5ZNC4A0A8I5ZNC4_RATRT1-M3-1349

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help