A0A8I5ZLT2 · A0A8I5ZLT2_RAT
- Proteinsteroid 11beta-monooxygenase
- GeneCyp11b2l1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids501 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 21-hydroxyprogesterone + 2 H+ + O2 + 2 reduced [adrenodoxin] = 18-hydroxy-11-deoxycorticosterone + H2O + 2 oxidized [adrenodoxin]This reaction proceeds in the forward direction.
- 21-hydroxyprogesterone + 2 H+ + O2 + 2 reduced [adrenodoxin] = corticosterone + H2O + 2 oxidized [adrenodoxin]This reaction proceeds in the forward direction.
Cofactor
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | corticosterone 18-monooxygenase activity | |
Molecular Function | heme binding | |
Molecular Function | iron ion binding | |
Molecular Function | steroid 11-beta-monooxygenase activity | |
Biological Process | glucocorticoid biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namesteroid 11beta-monooxygenase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A8I5ZLT2
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Sequence
- Sequence statusComplete
- Length501
- Mass (Da)57,461
- Last updated2022-05-25 v1
- Checksum5B5F2A736F5AE568
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P15393 | C11B1_RAT | Cyp11b1 | 499 | ||
A0A8I6AMK4 | A0A8I6AMK4_RAT | Cyp11b1 | 460 | ||
A0A0G2K9N5 | A0A0G2K9N5_RAT | Cyp11b1 | 499 | ||
D3ZCW0 | D3ZCW0_RAT | Cyp11b2l1 | 501 | ||
A0A8I5ZL64 | A0A8I5ZL64_RAT | Cyp11b1 | 451 |
Keywords
- Technical term