A0A8I5ZLE5 · A0A8I5ZLE5_RAT
- ProteinSolute carrier family 15 member 2
- GeneSlc15a2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids709 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- L-alanyl-L-alanine(out) + 2 H+(out) = L-alanyl-L-alanine(in) + 2 H+(in)This reaction proceeds in the forward direction.L-alanyl-L-alanine (out)CHEBI:195181
+ 2 H+ (out)CHEBI:15378= L-alanyl-L-alanine (in)CHEBI:195181+ 2 H+ (in)CHEBI:15378 - N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) + 3 H+(out) = N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in) + 3 H+(in)This reaction proceeds in the forward direction.
- a dipeptide(out) + 2 H+(out) = a dipeptide(in) + 2 H+(in)This reaction proceeds in the forward direction.
- an L-amino acid tripeptide(out) + 2 H+(out) = an L-amino acid tripeptide(in) + 2 H+(in)This reaction proceeds in the forward direction.
- carnosine(out) + 2 H+(out) = carnosine(in) + 2 H+(in)This reaction proceeds in the forward direction.
- glycyl-L-glutamate(out) + 3 H+(out) = glycyl-L-glutamate(in) + 3 H+(in)This reaction proceeds in the forward direction.
- glycyl-L-leucine(out) + 2 H+(out) = glycyl-L-leucine + 2 H+(in)This reaction proceeds in the forward direction.
- glycyl-L-lysine(out) + 2 H+(out) = glycyl-L-lysine(in) + 2 H+(in)This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Cellular Component | phagocytic vesicle membrane | |
Molecular Function | symporter activity | |
Biological Process | innate immune response | |
Biological Process | oligopeptide transport | |
Biological Process | peptide transport | |
Biological Process | protein transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSolute carrier family 15 member 2
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A8I5ZLE5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Apical cell membrane ; Multi-pass membrane protein
Cytoplasmic vesicle, phagosome membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 72-89 | Helical | |||
Transmembrane | 95-115 | Helical | |||
Transmembrane | 127-147 | Helical | |||
Transmembrane | 167-185 | Helical | |||
Transmembrane | 197-217 | Helical | |||
Transmembrane | 326-347 | Helical | |||
Transmembrane | 359-377 | Helical | |||
Transmembrane | 627-649 | Helical | |||
Transmembrane | 655-677 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-46 | Disordered | |||
Compositional bias | 13-27 | Polar residues | |||
Sequence similarities
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length709
- Mass (Da)79,283
- Last updated2022-05-25 v1
- Checksum867A9F871C7F8A00
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q63424 | S15A2_RAT | Slc15a2 | 729 | ||
A0A8I6AL86 | A0A8I6AL86_RAT | Slc15a2 | 189 | ||
A0A8I6A6Q4 | A0A8I6A6Q4_RAT | Slc15a2 | 741 | ||
A0A0H2UHA7 | A0A0H2UHA7_RAT | Slc15a2 | 740 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 13-27 | Polar residues | |||
Keywords
- Technical term