A0A8I5QKR3 · A0A8I5QKR3_HUMAN

  • Protein
    ATPase copper transporting alpha
  • Gene
    ATP7A
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATPase-coupled monoatomic cation transmembrane transporter activity
Molecular Functionmetal ion binding

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • ATPase copper transporting alpha

Gene names

    • Name
      ATP7A

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A8I5QKR3

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane447-469Helical
Transmembrane475-495Helical

Keywords

  • Cellular component

Disease & Variants

Variants

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The viewer provides 410 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)518PRIDEPhosphoserine
Modified residue (large scale data)520PRIDEPhosphoserine
Modified residue (large scale data)523PRIDEPhosphoserine
Modified residue (large scale data)531PRIDEPhosphothreonine
Modified residue (large scale data)532PRIDEPhosphoserine
Modified residue (large scale data)535PRIDEPhosphoserine
Modified residue (large scale data)551PRIDEPhosphoserine
Modified residue (large scale data)554PRIDEPhosphoserine
Modified residue (large scale data)557PRIDEPhosphoserine
Modified residue (large scale data)561PRIDEPhosphoserine
Modified residue (large scale data)568PRIDEPhosphoserine

Proteomic databases

Structure

3D structure databases

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    588
  • Mass (Da)
    63,023
  • Last updated
    2022-05-25 v1
  • Checksum
    364F4232A312F4C0
GKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQTSKVKVVVFDKTGTITHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTYESYELPARSQIGQKSPSEISVHVGIDDTSRNSPKLGLLDRIVNYSRASINSLLSDKRSLNSVVTSEPDKHSLLVGDFREDDDTAL

Computationally mapped potential isoform sequences

There are 17 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q04656ATP7A_HUMANATP7A1500
A0A8I5QJP0A0A8I5QJP0_HUMANATP7A457
A0A2R8YD60A0A2R8YD60_HUMANATP7A49
A0A8J9FM07A0A8J9FM07_HUMANATP7A1510
A0A8I5KQ62A0A8I5KQ62_HUMANATP7A972
A0A8I5KPN6A0A8I5KPN6_HUMANATP7A696
A0A8I5KQ07A0A8I5KQ07_HUMANATP7A70
A0A8I5KR00A0A8I5KR00_HUMANATP7A557
A0A8I5KU46A0A8I5KU46_HUMANATP7A475
A0A8I5KST1A0A8I5KST1_HUMANATP7A929
A0A8I5KVT9A0A8I5KVT9_HUMANATP7A766
A0A8I5KWA8A0A8I5KWA8_HUMANATP7A1531
A0A8I5KVB6A0A8I5KVB6_HUMANATP7A657
A0A8I5KWH1A0A8I5KWH1_HUMANATP7A586
A0A8I5KZ63A0A8I5KZ63_HUMANATP7A52
A0A8I5KXV0A0A8I5KXV0_HUMANATP7A1435
A0A8I5KY05A0A8I5KY05_HUMANATP7A844

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL356235
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AL645821
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AL772330
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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