A0A8I5NHC7 · A0A8I5NHC7_PAPAN
- ProteinRibosomal protein S6 kinase
- GeneRPS6KA3
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids740 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 74-82 | ATP (UniProtKB | ChEBI) | ||||
Sequence: LGQGSFGKV | ||||||
Binding site | 100 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Active site | 193 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 428-436 | ATP (UniProtKB | ChEBI) | ||||
Sequence: IGVGSYSVC | ||||||
Binding site | 451 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Active site | 539 | Proton acceptor | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | magnesium ion binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | intracellular signal transduction |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibosomal protein S6 kinase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Papio
Accessions
- Primary accessionA0A8I5NHC7
Proteomes
PTM/Processing
Keywords
- PTM
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-38 | Disordered | ||||
Sequence: MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEI | ||||||
Domain | 68-327 | Protein kinase | ||||
Sequence: FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFF | ||||||
Domain | 328-397 | AGC-kinase C-terminal | ||||
Sequence: STIDWNKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQ | ||||||
Domain | 422-679 | Protein kinase | ||||
Sequence: YEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWI |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length740
- Mass (Da)83,736
- Last updated2022-05-25 v1
- Checksum486AE8357CEAB6C8
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2I3MWU5 | A0A2I3MWU5_PAPAN | RPS6KA3 | 768 | ||
A0A8I5N0F6 | A0A8I5N0F6_PAPAN | RPS6KA3 | 711 | ||
A0A096N4X8 | A0A096N4X8_PAPAN | RPS6KA3 | 753 |
Keywords
- Technical term