A0A8I5KYW2 · A0A8I5KYW2_HUMAN

  • Protein
    Ubiquitin specific peptidase 54
  • Gene
    USP54
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    1/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functioncysteine-type deubiquitinase activity
Biological Processprotein deubiquitination

Names & Taxonomy

Protein names

  • Submitted names
    • Ubiquitin specific peptidase 54

Gene names

    • Name
      USP54

Organism names

Accessions

  • Primary accession
    A0A8I5KYW2

Proteomes

Organism-specific databases

Disease & Variants

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)424PRIDEPhosphoserine
Modified residue (large scale data)525PRIDEPhosphoserine
Modified residue (large scale data)546PRIDEPhosphoserine
Modified residue (large scale data)575PRIDEPhosphoserine
Modified residue (large scale data)578PRIDEPhosphotyrosine
Modified residue (large scale data)607PRIDEPhosphoserine
Modified residue (large scale data)612PRIDEPhosphoserine
Modified residue (large scale data)614PRIDEPhosphoserine
Modified residue (large scale data)617PRIDEPhosphoserine

Proteomic databases

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain31-352USP
Compositional bias382-434Basic and acidic residues
Region382-641Disordered
Compositional bias435-475Polar residues
Compositional bias478-503Basic and acidic residues
Compositional bias517-541Basic and acidic residues
Compositional bias604-621Polar residues
Compositional bias663-678Polar residues
Region663-726Disordered
Compositional bias679-713Basic and acidic residues

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    740
  • Mass (Da)
    83,755
  • Last updated
    2022-05-25 v1
  • Checksum
    3F087A7D6FF2BAB6
MSWKRNYFSGGRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRSFRQLTTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDTLRSALAKTFQDEQRFQLGIMDDAAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQMVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLMNAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYGKHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQDLPPQAEFQSYSRTCYDSEDSGHLTDSECNQKHTSKKGSLIERKRSSGRVRRKGDEPQASGYHSEGETLKEKQAPRNASKPSSSTNRLRDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQPDKKPPRTLPLHSRDWEIESTSSESKSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLSPFSEDSAKEFIPDEPSKPPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPRLIQRMESGYESSERNSSSPVSLDAALPESSNVYRDPSAKRSAGLVPSWRHIPKSHSSSILEVDSTASMGGWTKSQPFSGEEISSKSELDELQEEVARRAQEQELRRKREKELEAAKGFNPHPSRFMDLDELQNQVNSLSRSKYC

Computationally mapped potential isoform sequences

There are 14 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q70EL1UBP54_HUMANUSP541684
A0A7P0T9K1A0A7P0T9K1_HUMANUSP541637
A0A7P0T9N2A0A7P0T9N2_HUMANUSP541413
A0A804D9U3A0A804D9U3_HUMANUSP54837
R4GN32R4GN32_HUMANUSP54412
H7C296H7C296_HUMANUSP54358
H7C1E9H7C1E9_HUMANUSP54635
X6RHN7X6RHN7_HUMANUSP5480
X6RGF2X6RGF2_HUMANUSP54143
X6RH50X6RH50_HUMANUSP54153
A0A8I5KNN9A0A8I5KNN9_HUMANUSP54819
A0A8I5KRV2A0A8I5KRV2_HUMANUSP54113
A0A8I5KTP4A0A8I5KTP4_HUMANUSP541644
A0A8I5KYV7A0A8I5KYV7_HUMANUSP54797

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias382-434Basic and acidic residues
Compositional bias435-475Polar residues
Compositional bias478-503Basic and acidic residues
Compositional bias517-541Basic and acidic residues
Compositional bias604-621Polar residues
Compositional bias663-678Polar residues
Compositional bias679-713Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC073389
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AL359074
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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