A0A8I5KYR5 · A0A8I5KYR5_HUMAN
- ProteinMyosin XVB
- GeneMYO15B
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1437 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Features
Showing features for binding site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | myosin complex | |
Molecular Function | actin binding | |
Molecular Function | ATP binding | |
Molecular Function | cytoskeletal motor activity |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A8I5KYR5
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 1,644 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Proteomic databases
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-330 | Disordered | ||||
Sequence: MGRNQRKAPQRLERPGRPASGEQESGSASADGAPSRERRSDRGQADRAKPAAEPATAGGQGTPGGRRKPTAEGNGGCRRPGAGLSPKAQERQSNAQRQGRGPRGGRGGRLEEGSLSGGEELGGRRRRKRKDKGPSARRGRRTPRSLNGDTSGGDGGSSCPDSETREAQESGSQRGTARELRPTPEPTDMGSEGTKTGPESALEPSSDGLDSDWPHADTRGREGSSGTGPLGASEHSGGDSDSSPLGTGPGRGSRAAMASRTFEDSSRAPRDTGPAKDASDNRAQRGAEPETMQASTARAPRHQVGKAVGQVPAAAGEGEAGAAAGAGPED | ||||||
Compositional bias | 34-48 | Basic and acidic residues | ||||
Sequence: PSRERRSDRGQADRA | ||||||
Compositional bias | 145-177 | Polar residues | ||||
Sequence: SLNGDTSGGDGGSSCPDSETREAQESGSQRGTA | ||||||
Compositional bias | 264-284 | Basic and acidic residues | ||||
Sequence: DSSRAPRDTGPAKDASDNRAQ | ||||||
Region | 389-489 | Disordered | ||||
Sequence: RPPEGEGQGTGPRASEGWGRRKPDEGRGHGRGSKGRGRGKADEGRGHERGDEGRGRGKADEGRGHERGYEGRGCGKADEGRGHERGDEGRDHQRGYEGWGR | ||||||
Compositional bias | 405-489 | Basic and acidic residues | ||||
Sequence: GWGRRKPDEGRGHGRGSKGRGRGKADEGRGHERGDEGRGRGKADEGRGHERGYEGRGCGKADEGRGHERGDEGRDHQRGYEGWGR | ||||||
Region | 508-540 | Disordered | ||||
Sequence: GGMPRASPGGRSPQVPTSPVPGDPFDQEDETPD | ||||||
Region | 553-649 | Disordered | ||||
Sequence: AGRASSSRSSEEASADAPTGEGRGWPRAGVGGHSEGCRTSGEGVSGLRRGSLLAPTAPDGPSLDESGSSSEAELETLNDEPPVRWAQGSGPHEGPRL | ||||||
Domain | 720-1389 | Myosin motor | ||||
Sequence: EDMEDLARLRLVCDSSVLLCLKKRFHLGRIYTFGGPVLLVLNPHRSLPLFSPEVQASYHPRKALSTTPHIFAIVASAYDLAQNTGQDPCILLCGHSGSGKTEAAKKIMQFLSSLEQDQTGNRECQVEDMLPILSSFGHAKTILNANASRFGQVFCLYLQQGVIVGASVSHYLLETSRVVFQAQAERSFHVFYKLLAGLDSIERERLSLQGPETYYYLNQGQACRLQGKEDAQDFEGLLKALQGLGLCPEELNAVWAVLAAILQLGNICFSSSERESQEVAAVSSWAEIHTAARLLRVPPECLEGAVTRRVTETPYGQVSRSLPVESAFDARDALAKALYSRLFHRLLRRTNARLAPPGEGGSIGTVTVVDAYGFEALRVNGLEQLCNNLASERLQLFSSQMLLAQEEEECRRELLSWVPVPQPPRESCLDLLVDQPHSLLSILDAQTWLSQATDHTFLQKSHYHHGDHPSYAKPRLPLPVFTVRHYAGTVTYQVHKFLNRNRDQLDPAVVEMLGQSQLQLVGSLFQEAEPQSRGGRGRPTLASRFQQALEDLIARLGRSHVYFIQCLTPNPGKLPGLFDVGHVTEQLHQAAILEAVGTRSANFPVRVPFEAFLASFQALGSEGQEDLSDREKCGAVLSQVLGAESPLYHLGATKVLLQEQGWQRLEELRD | ||||||
Region | 1268-1290 | Actin-binding | ||||
Sequence: LEDLIARLGRSHVYFIQCLTPNP |
Sequence similarities
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,437
- Mass (Da)154,692
- Last updated2022-05-25 v1
- ChecksumDBCF2D7B8C5A9759
Computationally mapped potential isoform sequences
There are 16 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q96JP2 | MY15B_HUMAN | MYO15B | 3096 | ||
A0A286YF23 | A0A286YF23_HUMAN | MYO15B | 1589 | ||
A0A0J9YW04 | A0A0J9YW04_HUMAN | MYO15B | 278 | ||
A0A0J9YVN6 | A0A0J9YVN6_HUMAN | MYO15B | 20 | ||
A0A0J9YW50 | A0A0J9YW50_HUMAN | MYO15B | 1364 | ||
A0A0J9YWC2 | A0A0J9YWC2_HUMAN | MYO15B | 66 | ||
A0A0J9YX32 | A0A0J9YX32_HUMAN | MYO15B | 192 | ||
A0A0J9YXD6 | A0A0J9YXD6_HUMAN | MYO15B | 156 | ||
A0A0J9YXA6 | A0A0J9YXA6_HUMAN | MYO15B | 85 | ||
A0A0J9YXG9 | A0A0J9YXG9_HUMAN | MYO15B | 103 | ||
A0A0J9YXP9 | A0A0J9YXP9_HUMAN | MYO15B | 105 | ||
A0A0J9YXR1 | A0A0J9YXR1_HUMAN | MYO15B | 72 | ||
A0A0J9YY01 | A0A0J9YY01_HUMAN | MYO15B | 1389 | ||
A0A0J9YYB3 | A0A0J9YYB3_HUMAN | MYO15B | 101 | ||
A0A0J9YYJ7 | A0A0J9YYJ7_HUMAN | MYO15B | 760 | ||
A0A994J4K4 | A0A994J4K4_HUMAN | MYO15B | 106 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 34-48 | Basic and acidic residues | ||||
Sequence: PSRERRSDRGQADRA | ||||||
Compositional bias | 145-177 | Polar residues | ||||
Sequence: SLNGDTSGGDGGSSCPDSETREAQESGSQRGTA | ||||||
Compositional bias | 264-284 | Basic and acidic residues | ||||
Sequence: DSSRAPRDTGPAKDASDNRAQ | ||||||
Compositional bias | 405-489 | Basic and acidic residues | ||||
Sequence: GWGRRKPDEGRGHGRGSKGRGRGKADEGRGHERGDEGRGRGKADEGRGHERGYEGRGCGKADEGRGHERGDEGRDHQRGYEGWGR |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC087749 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF511237 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |