A0A8I5KY05 · A0A8I5KY05_HUMAN
- ProteinATPase copper transporting alpha
- GeneATP7A
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids844 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | Golgi apparatus | |
Cellular Component | membrane | |
Molecular Function | copper ion binding | |
Biological Process | copper ion transport | |
Biological Process | inorganic cation transmembrane transport | |
Biological Process | monoatomic cation transmembrane transport |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A8I5KY05
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 654-673 | Helical | ||||
Sequence: FLVSLFFCIPVMGLMIYMMV | ||||||
Transmembrane | 705-732 | Helical | ||||
Sequence: ILPGLSVMNLLSFLLCVPVQFFGGWYFY | ||||||
Transmembrane | 744-766 | Helical | ||||
Sequence: ANMDVLIVLATTIAFAYSLIILL |
Keywords
- Cellular component
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 620 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 150 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 152 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 244 | PRIDE | Phosphotyrosine | ||||
Sequence: Y | |||||||
Modified residue (large scale data) | 270 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 272 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 325 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 327 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 339 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 353 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 354 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 355 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 357 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 359 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 362 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 427 | PRIDE | Phosphoserine | ||||
Sequence: S |
Proteomic databases
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 8-74 | HMA | ||||
Sequence: NSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPKTLQEAIDDMGFDAV | ||||||
Domain | 85-151 | HMA | ||||
Sequence: TDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYPQKRTVAVTIIPSIVNANQIKELVPELSLDTG | ||||||
Domain | 171-237 | HMA | ||||
Sequence: VVLKMKVEGMTCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAF | ||||||
Domain | 277-343 | HMA | ||||
Sequence: STATFIIDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLY | ||||||
Domain | 377-443 | HMA | ||||
Sequence: QETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDAT | ||||||
Domain | 488-554 | HMA | ||||
Sequence: SKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGAT | ||||||
Domain | 564-630 | HMA | ||||
Sequence: GVLELVVRGMTCASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEAS |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length844
- Mass (Da)93,110
- Last updated2022-05-25 v1
- ChecksumD58E829DD46F8D5B
Computationally mapped potential isoform sequences
There are 17 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q04656 | ATP7A_HUMAN | ATP7A | 1500 | ||
A0A8I5QKR3 | A0A8I5QKR3_HUMAN | ATP7A | 588 | ||
A0A8I5QJP0 | A0A8I5QJP0_HUMAN | ATP7A | 457 | ||
A0A2R8YD60 | A0A2R8YD60_HUMAN | ATP7A | 49 | ||
A0A8J9FM07 | A0A8J9FM07_HUMAN | ATP7A | 1510 | ||
A0A8I5KQ62 | A0A8I5KQ62_HUMAN | ATP7A | 972 | ||
A0A8I5KPN6 | A0A8I5KPN6_HUMAN | ATP7A | 696 | ||
A0A8I5KQ07 | A0A8I5KQ07_HUMAN | ATP7A | 70 | ||
A0A8I5KR00 | A0A8I5KR00_HUMAN | ATP7A | 557 | ||
A0A8I5KU46 | A0A8I5KU46_HUMAN | ATP7A | 475 | ||
A0A8I5KST1 | A0A8I5KST1_HUMAN | ATP7A | 929 | ||
A0A8I5KVT9 | A0A8I5KVT9_HUMAN | ATP7A | 766 | ||
A0A8I5KWA8 | A0A8I5KWA8_HUMAN | ATP7A | 1531 | ||
A0A8I5KVB6 | A0A8I5KVB6_HUMAN | ATP7A | 657 | ||
A0A8I5KWH1 | A0A8I5KWH1_HUMAN | ATP7A | 586 | ||
A0A8I5KZ63 | A0A8I5KZ63_HUMAN | ATP7A | 52 | ||
A0A8I5KXV0 | A0A8I5KXV0_HUMAN | ATP7A | 1435 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL356235 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL645821 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AL772330 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |