A0A8I5KT00 · A0A8I5KT00_HUMAN

  • Protein
    Condensin-2 complex subunit D3
  • Gene
    NCAPD3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

function

Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcondensed chromosome, centromeric region
Cellular Componentcondensin complex
Cellular Componentnucleoplasm
Biological Processcell division
Biological Processmitotic chromosome condensation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Condensin-2 complex subunit D3

Gene names

    • Name
      NCAPD3

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A8I5KT00

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 1,600 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)516PRIDEPhosphothreonine
Modified residue (large scale data)517PRIDEPhosphoserine
Modified residue (large scale data)520PRIDEPhosphoserine
Modified residue (large scale data)523PRIDEPhosphoserine
Modified residue (large scale data)530PRIDEPhosphoserine
Modified residue (large scale data)531PRIDEPhosphoserine
Modified residue (large scale data)567PRIDEPhosphoserine
Modified residue (large scale data)1321PRIDEPhosphoserine
Modified residue (large scale data)1328PRIDEPhosphoserine
Modified residue (large scale data)1329PRIDEPhosphoserine
Modified residue (large scale data)1331PRIDEPhosphothreonine
Modified residue (large scale data)1334PRIDEPhosphothreonine
Modified residue (large scale data)1348PRIDEPhosphoserine
Modified residue (large scale data)1350PRIDEPhosphoserine
Modified residue (large scale data)1351PRIDEPhosphothreonine
Modified residue (large scale data)1357PRIDEPhosphoserine
Modified residue (large scale data)1370PRIDEPhosphoserine
Modified residue (large scale data)1372PRIDEPhosphoserine
Modified residue (large scale data)1379PRIDEPhosphothreonine
Modified residue (large scale data)1382PRIDEPhosphoserine
Modified residue (large scale data)1384PRIDEPhosphoserine

Proteomic databases

Interaction

Subunit

Component of the condensin-2 complex.

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias155-171Basic and acidic residues
Region155-188Disordered
Region514-533Disordered
Compositional bias889-906Polar residues
Region889-911Disordered
Domain957-1124Condensin complex subunit 1 C-terminal
Region1306-1339Disordered
Region1434-1484Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,484
  • Mass (Da)
    167,248
  • Last updated
    2022-05-25 v1
  • Checksum
    7D00C8335B7C33A4
MVALRGLGSGLQPWCPLDLRLEWVDTVWELDFTETEPLDPSIEAEIIETGLAAFTKLYESLLPFATGEHGSMESIWTFFIENNVSHSTLVALFYHFVQIVHKKNVSVQYREYGLHAAGLYFLLLEVPGSVANQVFHPVMFDKCIQTLKKSWPQESNLNRKRKKEQPKSSQANPGRHRKRGKPPRREDIEMDEIIEEQEDENICFSARDLSQIRNAIFHLLKNFLRLLPKFSLKEKPQCVQNCIEVFVSLTNFEPVLHECHVTQARALNQAKYIPELAYYGLYLLCSPIHGEGDKVISCVFHQMLSVILMLEVGEGSHRAPLAVTSQVINCRNQAVQFISALVDELKESIFPVVRILLQHICAKVVDKSEYRTFAAQSLVQLLSKLPCGEYAMFIAWLYKYSRSSKIPHRVFTLDVVLALLELPEREVDNTLSLEHQKFLKHKFLVQEIMFDRCLDKAPTVRSKALSSFAHCLELTVTSASESILELLINSPTFSVIESHPGTLLRNSSAFSYQRQTSNRSEPSGEINIDSSGETVGSGERCVMAMLRRRIRDEKTNVRKSALQVLVSILKHCDVSGMKEDLWILQDQCRDPAVSVRKQALQSLTELLMAQPRCVQIQKAWLRGVVPVVMDCESTVQEKALEFLDQLLLQNIRHHSHFHSGDDSQVLAWALLTLLTTESQELSRYLNKAFHIWSKKEKFSPTFINNVISHTGTEHSAPAWMLLSKIAGSSPRLDYSRIIQSWEKISSQQNPNSNTLGHILCVIGHIAKHLPKSTRDKVTDAVKCKLNGFQWSLEVISSAVDALQRLCRASAETPAEEQELLTQVCGDVLSTCEHRLSNIVLKENGTGNMDEDLLVKYIFTLGDIAQLCPARVEKRIFLLIQSVLASSADADHSPSSQGSSEAPASQPPPQVRGSVMPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRELEVCEDVAVRNNVIIVMCDLCIRYTIMVDKYIPNISMCLKDSDPFIRKQTLILLTNLLQEEFVKWKGSLFFRFVSTLIDSHPDIASFGEFCLAHLLLKRNPVMFFQHFIECIFHFNNYEKHEKYNKFPQSEREKRLFSLKGKSNKERRMKIYKFLLEHFTDEQRFNITSKICLSILACFADGILPLDLDASELLSDTFEVLSSKEIKLLAMRSKPDKDLLMEEDDMALANVVMQEAQKKLISQVQKRNFIENIIPIIISLKTVLEKNKIPALRELMHYLREVMQDYRDELKDFFAVDKQLASELEYDMKKYQEQLVQEQELAKHADVAGTAGGAEVAPVAQVALCLETVPVPAGQENPAMSPAVSQPCTPRASAGHVAVSSPTPETGPLQRLLPKARPMSLSTIAILNSVKKAVESKSRHRSRSLGVLPFTLNSGSPEKTCSQVSSYSLEQESNGEIEHVTKRAISTPEKSISDVTFGAGVSYIGTPRTPSSAKEKIEGRSQGNDILCLSLPDKPNKDTPACSRRSLRKTPLKTAN

Computationally mapped potential isoform sequences

There are 16 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P42695CNDD3_HUMANNCAPD31498
A0A8I5QKW0A0A8I5QKW0_HUMANNCAPD3280
A0A8I5QKQ4A0A8I5QKQ4_HUMANNCAPD3137
A0A8I5QL00A0A8I5QL00_HUMANNCAPD3130
A0A8I5QKI5A0A8I5QKI5_HUMANNCAPD3119
G3V1A9G3V1A9_HUMANNCAPD31084
E9PQA3E9PQA3_HUMANNCAPD3319
E9PL95E9PL95_HUMANNCAPD366
E9PLE0E9PLE0_HUMANNCAPD3565
E9PJM8E9PJM8_HUMANNCAPD337
E9PKK4E9PKK4_HUMANNCAPD3832
A0A8I5KR13A0A8I5KR13_HUMANNCAPD375
A0A8I5KRL1A0A8I5KRL1_HUMANNCAPD3122
A0A8I5KTD5A0A8I5KTD5_HUMANNCAPD3132
A0A8I5KTC8A0A8I5KTC8_HUMANNCAPD356
A0A8I5KYN6A0A8I5KYN6_HUMANNCAPD3183

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias155-171Basic and acidic residues
Compositional bias889-906Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP000859
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AP001775
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
KF511144
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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