A0A8I5KT00 · A0A8I5KT00_HUMAN
- ProteinCondensin-2 complex subunit D3
- GeneNCAPD3
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1484 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | condensed chromosome, centromeric region | |
Cellular Component | condensin complex | |
Cellular Component | nucleoplasm | |
Biological Process | cell division | |
Biological Process | mitotic chromosome condensation |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameCondensin-2 complex subunit D3
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A8I5KT00
Proteomes
Organism-specific databases
Subcellular Location
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 1,600 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | ||
---|---|---|---|---|---|---|
Modified residue (large scale data) | 516 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 517 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 520 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 523 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 530 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 531 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 567 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 1321 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 1328 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 1329 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 1331 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 1334 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 1348 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 1350 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 1351 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 1357 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 1370 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 1372 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 1379 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 1382 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 1384 | PRIDE | Phosphoserine | |||
Proteomic databases
Interaction
Subunit
Component of the condensin-2 complex.
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 155-171 | Basic and acidic residues | |||
Region | 155-188 | Disordered | |||
Region | 514-533 | Disordered | |||
Compositional bias | 889-906 | Polar residues | |||
Region | 889-911 | Disordered | |||
Domain | 957-1124 | Condensin complex subunit 1 C-terminal | |||
Region | 1306-1339 | Disordered | |||
Region | 1434-1484 | Disordered | |||
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,484
- Mass (Da)167,248
- Last updated2022-05-25 v1
- Checksum7D00C8335B7C33A4
Computationally mapped potential isoform sequences
There are 16 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P42695 | CNDD3_HUMAN | NCAPD3 | 1498 | ||
A0A8I5QKW0 | A0A8I5QKW0_HUMAN | NCAPD3 | 280 | ||
A0A8I5QKQ4 | A0A8I5QKQ4_HUMAN | NCAPD3 | 137 | ||
A0A8I5QL00 | A0A8I5QL00_HUMAN | NCAPD3 | 130 | ||
A0A8I5QKI5 | A0A8I5QKI5_HUMAN | NCAPD3 | 119 | ||
G3V1A9 | G3V1A9_HUMAN | NCAPD3 | 1084 | ||
E9PQA3 | E9PQA3_HUMAN | NCAPD3 | 319 | ||
E9PL95 | E9PL95_HUMAN | NCAPD3 | 66 | ||
E9PLE0 | E9PLE0_HUMAN | NCAPD3 | 565 | ||
E9PJM8 | E9PJM8_HUMAN | NCAPD3 | 37 | ||
E9PKK4 | E9PKK4_HUMAN | NCAPD3 | 832 | ||
A0A8I5KR13 | A0A8I5KR13_HUMAN | NCAPD3 | 75 | ||
A0A8I5KRL1 | A0A8I5KRL1_HUMAN | NCAPD3 | 122 | ||
A0A8I5KTD5 | A0A8I5KTD5_HUMAN | NCAPD3 | 132 | ||
A0A8I5KTC8 | A0A8I5KTC8_HUMAN | NCAPD3 | 56 | ||
A0A8I5KYN6 | A0A8I5KYN6_HUMAN | NCAPD3 | 183 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 155-171 | Basic and acidic residues | |||
Compositional bias | 889-906 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP000859 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AP001775 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF511144 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |