A0A8I3Q8L3 · A0A8I3Q8L3_CANLF

Function

Catalytic activity

Features

Showing features for binding site.

1794100200300400500600700
TypeIDPosition(s)Description
Binding site36ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionprotein kinase activity
Biological ProcessDNA damage response
Biological Processmitotic cell cycle
Biological Processpositive regulation of DNA-templated transcription
Biological Processregulation of cellular senescence

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • Name
      NEK4

Organism names

  • Taxonomic identifier
  • Strain
    • Labrador retriever
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Canidae > Canis

Accessions

  • Primary accession
    A0A8I3Q8L3

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain6-261Protein kinase
Region296-316Disordered
Compositional bias380-397Basic and acidic residues
Region380-530Disordered
Compositional bias398-427Polar residues
Compositional bias448-464Basic and acidic residues
Compositional bias487-511Basic and acidic residues
Region553-614Disordered
Compositional bias565-580Basic and acidic residues
Compositional bias582-614Polar residues
Region631-658Disordered
Compositional bias643-657Basic and acidic residues

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    794
  • Mass (Da)
    89,705
  • Last updated
    2022-05-25 v1
  • Checksum
    C9C360DEE0F0828A
MPLAAYCYLRVVGRGSYGEVTLVRHRRDGRQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKERKGQLLPESQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENNGDMANTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPKDYSPELSELIRTMLSKRPEERPSVRSILRQPYIKHQISLFLEATKAKTSKSNIKSSDSKSKPVATVVSGNAESSHKVVPLQPQSSEGSKTYVMGEDKCLSQEKPIVIDPLKTPASLKGHNCKPDVSDTSESLATISKVNIDILPAERRDSLSDGLVRENQPRHLDTSNELEGKCSISQVKEKLQDGTEPSAQPRNVIPAWFSNDVTGERSDPARPLQPLNKDQKPKDQDQVANECVTEKPDRTLSGLQPHSFGSEPSLSRQRRQKKREQPKHSGEERQVSRDLCRFQEAPPRLLPSLPTAGKKDVTLTQKDAENQSRLVIGSAVSSLRSKEVSSSKDQPLSARERRRLKQSQEEMFPSGPSVRRSLSASGPGNSQEEGQPTPALWSSDCSVAQERKLIRCLSEDELSSSTSSTDKSDGDSKERKCHTNEMSDLVQLMTQTLKLESKESCEDLLVPDPVSEFKLHRKYRDTLILHGKVVEEAEDLHFKQLPSAVMPGSEKIRRIVEVLRADVIQGLGIQLLEQVYDLLEEEDELQREVRLQEHMGEKYTTYSVKARQLKFFEENVNF

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8I3S7B7A0A8I3S7B7_CANLFNEK4705

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias380-397Basic and acidic residues
Compositional bias398-427Polar residues
Compositional bias448-464Basic and acidic residues
Compositional bias487-511Basic and acidic residues
Compositional bias565-580Basic and acidic residues
Compositional bias582-614Polar residues
Compositional bias643-657Basic and acidic residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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