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A0A8I1Z5Q3 · A0A8I1Z5Q3_ACIBA

  • Protein
    Histidine biosynthesis bifunctional protein HisIE
  • Gene
    hisI
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.
Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionphosphoribosyl-AMP cyclohydrolase activity
Molecular Functionphosphoribosyl-ATP diphosphatase activity
Biological ProcessL-histidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Histidine biosynthesis bifunctional protein HisIE

Including 2 domains:

  • Recommended name
    Phosphoribosyl-AMP cyclohydrolase
  • EC number
  • Short names
    PRA-CH
  • Recommended name
    Phosphoribosyl-ATP pyrophosphatase
  • EC number
  • Short names
    PRA-PH

Gene names

    • Name
      hisI
    • Synonyms
      hisIE
    • ORF names
      IAG11_00880

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • A86
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex

Accessions

  • Primary accession
    A0A8I1Z5Q3

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-148Phosphoribosyl-AMP cyclohydrolase
Region149-257Phosphoribosyl-ATP pyrophosphohydrolase

Sequence similarities

In the C-terminal section; belongs to the PRA-PH family.
In the N-terminal section; belongs to the PRA-CH family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    257
  • Mass (Da)
    29,208
  • Last updated
    2022-01-19 v1
  • MD5 Checksum
    5DD949DBD27DE2B7C9BB098372727039
MNNTQWLDEVKFNEQGLIPAIAQHHQTGRILMVAWMNRESLALTAEKNQAVYFSRSRQKLWHKGEESGHFQTVYEIRLDCDGDVIILQVEQHGGIACHTGRESCFYRKLTPQGWEIVDAQLKDPTAIYGDKAKTESHDHAHTTEQVDVLAHLGQLMQERKQAEADTSYVASLYKKGINKILEKVGEEGVETIIAAKDYAAQNTESNLNDLIYETADLWFHSIVMLGYFDLNPQLIIDELARRQGLSGLVEKANRNKV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACSVK010000001
EMBL· GenBank· DDBJ
MBD0218454.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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