A0A8I1FU73 · A0A8I1FU73_ENTAS

  • Protein
    DNA polymerase III subunit gamma/tau
  • Gene
    dnaX
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentDNA polymerase III complex
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Molecular FunctionDNA-directed DNA polymerase activity
Molecular Functionmetal ion binding
Biological ProcessDNA-templated DNA replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA polymerase III subunit gamma/tau
  • EC number

Gene names

    • Name
      dnaX
    • ORF names
      JGT27_03495

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 170C2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Enterobacter > Enterobacter cloacae complex

Accessions

  • Primary accession
    A0A8I1FU73

Proteomes

Subcellular Location

Interaction

Subunit

DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain37-178AAA+ ATPase
Region383-441Disordered
Compositional bias384-400Pro residues
Compositional bias401-423Polar residues

Sequence similarities

Belongs to the DnaX/STICHEL family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    642
  • Mass (Da)
    70,662
  • Last updated
    2022-01-19 v1
  • Checksum
    EA4242CD13F2C7F9
MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPAHVKFLLATTDPQKLPVTILSRCLQFHLKALDVEQIRAQLEHILDEEKIVHEPRALQLLARAADGSLRDALSLTDQAIASGDGKLSTEAVSTMLGTLDDDQALSLIEAMIAANGERVMSQVNAAAARGIEWEGLLVEMLSLLHRVAMLQLSPSAIGADMAAIEQRMRELARTVPPADVQLYYQTLLIGRKELPFAPDPRMGVEMTLLRALAFHPRMPLPEPEAPRQSFAPVAPTAVMSPQQVPPQPTPPPQQNVPLSDATSSVLAARSQLQRAQGVTKPKKSEPAAPGRARPVNNAALERLASVTERVQSRPAPSALEQKAPVKEEAYRWKATTITEEVKEEVATPKALKKALEHEKTPELSAKLAEESIVRDAWAAEVSKLQLPKLVEQVALNAWKEQDGNQVRLHLRPGQRHLNSPGAQKALAEALTALQGAPVELTIIEDDNPAVRTPLEWRQAIYEEKLAQAREAIIADNNIQTLRRFFDADLDEESIRPI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias384-400Pro residues
Compositional bias401-423Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAELXN010000011
EMBL· GenBank· DDBJ
MBJ6594754.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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