A0A8H9Z3U7 · A0A8H9Z3U7_9PSED

  • Protein
    Oxygen-dependent choline dehydrogenase
  • Gene
    betA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site6-35FAD (UniProtKB | ChEBI)
Active site475Proton acceptor

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functioncholine dehydrogenase activity
Molecular Functionflavin adenine dinucleotide binding
Biological Processglycine betaine biosynthetic process from choline

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Oxygen-dependent choline dehydrogenase
  • EC number
  • Short names
    CDH
    ; CHD
  • Alternative names
    • Betaine aldehyde dehydrogenase
      (BADH
      ) (EC:1.2.1.8
      ) . EC:1.2.1.8 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      betA
    • ORF names
      HU735_00280

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BW16M2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A8H9Z3U7

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain84-107Glucose-methanol-choline oxidoreductase N-terminal
Domain261-275Glucose-methanol-choline oxidoreductase N-terminal

Sequence similarities

Belongs to the GMC oxidoreductase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    565
  • Mass (Da)
    62,539
  • Last updated
    2022-01-19 v1
  • MD5 Checksum
    B6D982E3D9CE89B2ED9F95F6E2679481
MSQEFDYIIVGAGSAGNTLATRLTEDASVTVLLLEAGGPDYRFDFRTQMPAALAFPLQGRRYNWAYETDPEPHMDGRRMECGRGKGLGGSSLINGMCYIRGNAMDFDGWAELPGLEDWTYLDCLPYFRKAETRDIGPNDYHGGEGPVSVATPKAGNNPLFHAMVEAGVQAGYPRTEDLNGYQQEGFGPMDRSVTKNGRRSSTARGYLDQAKKRPNLTIVTHALSDRVLFDNKRAVGVTYLVGDSEERVEARARKEVIVSSGAIASPQLLQRSGVGPRALLESLDIPVVHDLPGVGENLQDHLELYLQYACTQPVSLYPSLLWWNQPKIGAEWLFNGTGIGASNQFEAGGFIRTRPEFKWPNIQYHFLPVAINYNGSNGVKEHGFQAHMGSMRSPARGRIQAKSKNPRQHPSILFNYMSTEQDWQEFRDGIRLTREIMAQPALDAFRGREISPGAHVQTDEELDKFIREHAETAFHPSCSCKMGTDDMAVVDGEGRVHGMQGLRVVDASIMPLIITGNLNATTIMIAEKISDKIRGRKPLPRSTAKYYVAGDAPVKGKPMREVKQA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABWRI010000001
EMBL· GenBank· DDBJ
MBC3433831.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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