A0A8H8A424 · A0A8H8A424_9ASCO

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site300Nucleophile
Active site384
Active site386

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionamino acid binding
Molecular Functionaspartate carbamoyltransferase activity
Molecular FunctionATP binding
Molecular Functioncarbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Molecular Functiondihydroorotase activity
Molecular Functionmetal ion binding
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process
Biological Processcitrulline biosynthetic process
Biological Processglutamine metabolic process
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aspartate carbamoyltransferase

Gene names

    • ORF names
      PMAC_000506

Organism names

  • Taxonomic identifier
  • Strain
    • P2C
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Taphrinomycotina > Pneumocystomycetes > Pneumocystaceae > Pneumocystis

Accessions

  • Primary accession
    A0A8H8A424

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain559-751ATP-grasp
Domain1094-1285ATP-grasp
Domain1349-1503MGS-like

Sequence similarities

In the 2nd section; belongs to the CarB family.
In the 3rd section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
In the C-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
In the N-terminal section; belongs to the CarA family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,213
  • Mass (Da)
    248,055
  • Last updated
    2022-01-19 v1
  • MD5 Checksum
    F48A7B3A1716BAF2E58E383DB76885E6
MLIKPASSETPTSINNNAKKVILELDDGIAYQGYSFGAEKSVSGELVFQTGMVGYNESITDPSYKGQILIFTFPLVGNYGVPSRKKMYPSLSDIPLYFESRKIHVSALVVASYSRSYSHYLSESTLGDWLREQGIPAICGVDTRALTKKIRARGSILGRLLQMKQGCVLDDFFDDNVSWRDKFENIEWVNPNLRNLVQEVSIPTVRIYKPLSECSQKLLSGEQLRILCVDVGMKASQILCFLKRGVELKVVPWDYDFSLEKDYHGLFISNGPGDPSILTIVIERLKKCIDAKMTPIFGICLGHQLLSRAAGAETIKMKFGNRGQNIPCTNMINGRCYITSQNHGYAVDASTLPQDWKEFYVNINDGSNEGIYHTTLPFFSLQFHPESAPGPRDTEFMFDVFIDVVKRSFNENRLVSFEIPQEKVKDNLSNLRVNIKKVLILGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATVQTSKGLADKVYFLPVNPEFVLKVIKYEIPDAIYLTFGGQTALNVGVRLKDEFEKLGVRVLGTPIDTIITTEDRQLFAKSMKEINEKCAASASASNIQDAMKVGSDIGYPVIVRAAYALGGLGSGFADNVEQLCALCSKAFAVSPQVLIEKSMKGWKEIEYEVVRDCKDNCIAVCNMENFDPLGIHTGDSVVVAPSQTLSNEDYNMLRTTAINVVRHLGVIGECNIQYALNPFLKEYYIIEVNARLSRSSALASKATGFPLAFIAAKLGLGITLNELKNAVTKETSICFEPSLDYVVVKIPRWDLKKFTRVNTQLNSSMKSVGEVMSIGRTFEETIQKAIRAIDYNNLGFNETDALMSLDMELQTPSDQRMFAIANAMYAGYSVDRIWELTKIDKWFLDRLMGLINLEKKIREYTLHNIPIQLLFHAKRFGYSDRQLAKFLGSNELAVRKKRIDSGITPFVKQIDTVAAEFPAYTNYLYMTYNACEHDISFEDHGVMVLGSGVYRIGSSVEFDWCAVCAIRTVRERGIKTIMVNYNPETVSTDYDEADRLYFENISLERVLDIYDIENSTGIIVSMGGQIPNNIALSLHRLNVKILGTSPEMIDSAENRYKFSRMLDRIGIDQPLWKELTSIDEASDFCESVTYPVLVRPSYVLSGAAMNTVYSRDDLANYLKQAVDVSKEHPVVITKYIEGAKEIELDAVAKDGKMVIHFITEHVENAGVHSGDATLILPPQDLDPETVYRIEQASIQIANALNVTGPFNIQFIAKDNEIKVIECNVRVARSWPFVSKVSGVDLVQIATDVILGFSDSSYPVINMPHNYVGVKVPQFSFSRLSGADPVLGVEMASTGEVASFGKDKYEAYLKALVSTGIQLPKKNILLSIGSFKEKTEMLESVIKLYKLGYTLFATAGTADFIHEHGIPVKYLEALPEDQKDQKSEYSLTQHLSKNLIDMYINLPSNNRFRRPANYTSIGYRTRRMAVDYSIPLITNVKCAKLMIEALSRISSIDISPIDFQTSYNSITLPGFIDISAFVPQMSQIDFFDFDDVTKRYIASGFTTICLVPIELDNSVINANSVPIKAFDAKKSVHCDYALLVAAASDNLTYLDQISTSVKSVFIPFNFLFENIGKLTLFISHFSSWPNIKIIVTDAKGAYLASVLFLANLYNIAIHISNVTTRDDILLISLSKKKGLKVTCDVSVYALFLSQSDIYKFKFLPTDIDQKSLWEHMEIIDCFSVGSLPYQIAYELNQTDFSCVRISDTLPLLFTAMTDKRLTLDDILLRLYYNPKSIFGIPEQVNTFLEVEIDRNYILNSSDGWSPFIGKKMIGSIHRVVFNGQTTYLDGKFFPNYQGKDISLILSSSILPSTDIPTIYAKKDANLRPFVFSPGPLNDLTFPLAVSEQFKKKYESFGPRVSDTTTLFSLIKNTNFFRKNIVSVQQFNRRDLHLLFAIAHEMRIAVERQGILDILASKVLCMIFFEPSTRTSTSFDAAMQRLGGRVVSVTVSASSVKKGESLADTIRTLGCYGDAILIRHPSEDSANIAAKYSPVPIINGGNGSFEHPTQAFLDLYTIREELGTVNGLNVTFVGDLKYGRTVHSLIKLLRFYQVEVNLVSPRELALPEDIKKFILDQGQVINEYYTLNEDIIAITDVLYCTRVQGERFSDSKEYEKLKNSFTIDNDILLKAKSHMIIMHPFPRNNEISEEVDFDQRAAYFREMKYGMFIRMALLVAVLGTNERV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABMLO010000012
EMBL· GenBank· DDBJ
KAG5513884.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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