A0A8H7RBU1 · A0A8H7RBU1_9FUNG

  • Protein
    Aspartate carbamoyltransferase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site349Nucleophile
Active site433
Active site435

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionamino acid binding
Molecular Functionaspartate carbamoyltransferase activity
Molecular FunctionATP binding
Molecular Functioncarbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Molecular Functiondihydroorotase activity
Molecular Functionmetal ion binding
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process
Biological Processcitrulline biosynthetic process
Biological Processglutamine metabolic process
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aspartate carbamoyltransferase

Gene names

    • ORF names
      INT47_006157

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • WA0000017839
  • Taxonomic lineage
    Eukaryota > Fungi > Fungi incertae sedis > Mucoromycota > Mucoromycotina > Mucoromycetes > Mucorales > Mucorineae > Mucoraceae > Mucor

Accessions

  • Primary accession
    A0A8H7RBU1

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain609-801ATP-grasp
Domain1146-1337ATP-grasp
Domain1403-1568MGS-like
Region1877-1900Disordered

Sequence similarities

In the 2nd section; belongs to the CarB family.
In the 3rd section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
In the C-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
In the N-terminal section; belongs to the CarA family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,249
  • Mass (Da)
    247,335
  • Last updated
    2022-01-19 v1
  • Checksum
    0FBAEECDC4C285CF
MVSNIPVPTINGIAPMVLAAHITAPAANATPIARSPRSPTAPHRPAAALEDPKDVTTAAFVLKDGTSFQGISFGSETQSISGECVFQTGMVGYPESLTDPSYRGQILVVTFPLVGNYGVPSRTEMDELLTDLPKRFESNQIHVAGLIVGSYATDYSHYLAESSLATWLKENNVPALYGIDTRAMTKKIRDQGVTLAKILFPKKSAGNGLDHAALGLSIQDDGLERWMNDYETVEWVDPNERNLVAEVSIKEPKVYYPDPKNAIKTPSGRTMRVIAVDIGMKYNQIRCFVYRGVELKVVPWDYDFNAEPVDSYDGLFLSNGPGDPTTIELTISRVRTYIQNIKKPIFGICLGHQVMALASGAKTIKMKYGNRGHNIPCTNMISGRCYITSQNHGYAVDASTLPENFSELFVNANDGSNEGLIHEKLPIFSVQFHPESTPGPRDTEFLFDVFIQNIKECLNTKSLVPVQMPGGTKAENIKKNPRVHVEKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTVLINPNIATIQTSKGLADKVYFLPVTPEFVRKVIEFEKPDGIYVTFGGQTALSVGIALKDEFEALGVKVLGTQIDTVITTEDRDLFAQALYEIDEKCAPSASAVTVEESITAANNIGYPVIVRAAYALGGLGSGFADNDKELIALCNKAFATSPQVLIEKSMKGWKEIEYEVVRDCQDNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPFSKEYCIIEVNARLSRSSALASKATGYPLAFVAAKLGLGIPLNEIKNSVTKVTCACFEPSLDYVVVKIPRWDLKKFNRVSTALSSSMKSVGEVMAIGRTFEETMQKAIRAIDYNLDGFVSSDIIKDEDIEYELTHPSDQRLFAIANAMEKGYTVDRIWELTKIDKWFLNKLMRINNLGDRLTGFTKANLPGNLIRSAKQLGFSDRQIANRINSNELAVRRLRQEFGVTPFVKQIDTVAAEFPAFTNYLYMTYNAVEHDITFDDNGVMVLGSGVYRIGSSVEFDWCAVRAIRTLREQKIKTVMVNYNPETVSTDYDEADRLYFENINMERVLDIYEIEKSSGVLMAMGGQTPNNIALPLHRQNVKVLGTSPEMIDNAENRYKFSRMCDNIGVDQPLWKELTSYEEAEVFCEKVGYPVLVRPSYVLSGAAMNVVSSKDDLESYLKEAAAVSRDYPVVISKYIEDAKEIEMDAVALDGKMIMHVVSEHVENAGVHSGDATLILPPQDLDPETVRKIEVATAKIGRALNITGPFNIQFIAKDNEIKVIECNVRAARSFPFVSKVTGIDLVEMATLAMLGLPVTPYPKIAMPKDYVGIKVPQFSFSRLSGADPILGVEMASTGEVACFGKDKYQAYLKALLATGFSLPKKNILFSIGSYKEKIEMLPSVKRLHELGYSLFATTGTADFISEHGIPVKHLDTLDADTDDQIKAEYSLQQHLSNNMIDLYVNLPSRNRFRRPASYMSKGYRSRRMAVDYDIPLLTNVKCAKLFVEALARKKDFEILGIDFKSSSNTATLPGLFNINAFLPSTEDLATVTNTSLKSGFTTISAVCDDVKDQASLETMSSAAHKNASVDYLLSITATAENADQLDSVASEAAAVYIDTDKIGSGNVSVFDSVFDSWPSNQVMITEAKATDLASILLLASIHSRVIHVSNVTTKDDLALIEMTKNKGLKVTCDVSIYSLFLNKSDVDSKLLPSVADQEGLWKKLHVIDCFSVGSTPAKLDSTSNAAGIAEALPLLLTAVAQGRLTIQDISERMNDNPRRIFGLSPQTDTYIDVELDRSKAWTTGPLAGKKTQGSISRVVVNGTTVFMDGVLRVAGSLGRDLSVQAKAAELVVPAPKKKADSTPSDADISDVPETAPERKSIQPFDPIKLAGASDQQLVAFATPSYEISASLARVVSRSPFYRKHILRSKQFDRSDLHLLFGVAHEMRNMVELYGSINLLQGRVMSTMFFEPSTRTSCSFEAAMYRLGGKVVSVSATTSSVQKGETLSDTVRTLGCYTDLIVLRHPQPGSAQIAAKHSKVPIINAGDGIGEHPTQAFLDVFTIREELGTVNGLSITMVGDLKNGRTVHSLVKILAYYQVTINYVCPDSLAMPKDVMEEVAAAGITQNVYASLDEVIGITDVLYMTRVQKERFDTEEEYRRVKDAYILNNNVLSKAKSQMIIMHPLPRVNEIEPEVDFDQRAAYFRQMRYGLYVRMALLALVMGTHRG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAEPRD010000020
EMBL· GenBank· DDBJ
KAG2208301.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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