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A0A8H7NX40 · A0A8H7NX40_9APHY

  • Protein
    Elongation factor G, mitochondrial
  • Gene
    MEF1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Pathway

Protein biosynthesis; polypeptide chain elongation.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site55-62GTP (UniProtKB | ChEBI)
Binding site132-136GTP (UniProtKB | ChEBI)
Binding site186-189GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functiontranslation elongation factor activity
Biological Processmitochondrial translational elongation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Elongation factor G, mitochondrial
  • Short names
    EF-Gmt
  • Alternative names
    • Elongation factor G 1, mitochondrial
      (mEF-G 1
      )
    • Elongation factor G1

Gene names

    • Name
      MEF1
    • ORF names
      IEO21_07978

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • FPRL280
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Polyporales > Postiaceae > Postia

Accessions

  • Primary accession
    A0A8H7NX40

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-22
ChainPRO_503445608223-753Elongation factor G, mitochondrial

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain46-335Tr-type G

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    753
  • Mass (Da)
    83,612
  • Last updated
    2022-01-19 v1
  • MD5 Checksum
    8B7043B62AD4B45C614B8332A9329EF4
MSCRRADCVLLVLLDDHAAAVAERPAEELPAVEAYPLSDQDLRRLRFQRNIGVSAHIDSGKTTLTERILYYTGRIREIHEVRGRDNVGAKMDSMDLEREKGITIQSAATFCDWVATMPATGEREEYAINIIDTPGHVDFTIEVERALRVLDGAILVLCAVSGVQSQTTTVDRQMRRYNVPRISFINKMDRPGANPWRVIEQIRTKLHIPAAAVQVPIGVEDELKGVVDLVRWKAVYNEGEKGNNLAESDEIPATVLELAKAKRRELLEQLADVDDEIGEMLIMDEEPNTQQLAEAIRRATVGLRFSPVFMGSAVKNMSVQPLLDGVCAYLPMPSEADVVAHDTSLPTDAPMVPLVPASGAPLVALAFKLEEGRFGQLTYMRVYQGTMRKGQFIYHGRTGKKVKVPRLVRMHSNEMEDIEEIGPGEICAIFGVDCASGDTFTDGSTSYSMTSMFVPEPVISLALKPVGQETPNFSRALNRFQKEDPTFRVHIDKESKETIISGMGELHLEIYVERMKREYNVECTTGKPRVAFRETITQRADFHYTHKKQTGGAGQYARVIGYVEPMEPDPKTGKDVAFENFVMGGNIPSSYIPACEKGFYEALEKGSLSGNPVSGSRLVLQDGLAHSVDSSELAFRLAVIGAFREIYAKTKPVILEPIMKVEVVAPSEFQSAVIGGLNQRRGTITDSEVREDEFTAIAEVALNDMFGYSSHLRGVTQGKGEFSMEYKCHQPVLPNIQKELEDAYKKTLPQSKK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JADOXO010000252
EMBL· GenBank· DDBJ
KAF9808124.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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