A0A8H7F2A9 · A0A8H7F2A9_AGABI

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Probably binds two magnesium or manganese ions per subunit.

Features

Showing features for binding site, active site, site.

1904100200300400500600700800900
TypeIDPosition(s)Description
Binding site514Mg2+ 1 (UniProtKB | ChEBI)
Binding site549Mg2+ 1 (UniProtKB | ChEBI)
Active site627
Active site662Proton donor/acceptor
Binding site662Mg2+ 1 (UniProtKB | ChEBI)
Binding site664Mg2+ 1 (UniProtKB | ChEBI)
Site664Transition state stabilizer
Site723Important for catalytic activity
Binding site748Mg2+ 1 (UniProtKB | ChEBI)
Active site749Proton acceptor
Binding site749Mg2+ 1 (UniProtKB | ChEBI)
Site749Interaction with DNA substrate

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-(apurinic or apyrimidinic site) endonuclease activity
Molecular Functiondouble-stranded DNA 3'-5' DNA exonuclease activity
Molecular Functionmetal ion binding
Molecular Functionphosphoric diester hydrolase activity
Biological Processbase-excision repair

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Endonuclease/exonuclease/phosphatase domain-containing protein

Gene names

    • ORF names
      Agabi119p4_5647

Organism names

  • Taxonomic identifier
  • Strain
    • H119_p4
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Agaricineae > Agaricaceae > Agaricus

Accessions

  • Primary accession
    A0A8H7F2A9

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-23Disordered
Compositional bias413-442Polar residues
Region413-504Disordered
Compositional bias450-483Polar residues
Domain512-733Endonuclease/exonuclease/phosphatase

Sequence similarities

Belongs to the DNA repair enzymes AP/ExoA family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    904
  • Mass (Da)
    101,625
  • Last updated
    2022-01-19 v1
  • Checksum
    7DC50C1A365F57E2
MDGDEPHQGVKDSIHNPNKSNRYLQLTGEPQQEETMEVNERVDPALSHTVKDNKITIRGLVYTAPPIGGFPTPQVTSPVTRGLPTSLIETFDSIPGLKIWVRPWGAYYSTDLQTIRLSVAKTLTDFLGKEELVNLFQPDAEKKDRHDPGGAPWHFLVTNLTQDEHNIAVMTKVIASKRATLFLLPYTQPIPSFVMLLKNITYDDGHEVNGEDRVVKAVSDTLISTPLLDRDLMSLVEKPHRAGLELDLFIQGLEASLYKLNLDTKGPTHVWKISSTKMPSFSSIHSYNRFVSRLLELNYPTTGYGTGQPATGPENYGCQMCKSRDHMKVECPFPVIPGWMTPADEQIPWLLNASKREKAGRGATIRNKKETQEAEISPLGPNIPMEVVLNHQSKGKPELRVTSATTTLNNANLDESTTLNSVTNVPGPWSGGSDNQAAGLAPNETTGFLAGGNPGAQDNSTVLIERQQENQLEEPGTTNYNDGANRRKKSKNHNPNLSKPQKDTRANIKIGSLNINGHGARSIFDPKNKWLKINQLMREERMSILAVQEAHIDSEGADELNSLFKNTTILPSPNLGNLNSKGVAFVINQRLAAVGQNMKSTVIIPGRALLLETRWHNNETLTILNIYAPNDTLENKEFWSTLEEKWAEISSTYPFPDLMLGDFNLTEEGIDRNNGRIDNQGAIENLKSLCSFFELSDGWRLRNPLERDFTLRHLSSNHQSRIDRIYVSNEILNQAQDWEISTPALQTDHRLISLQIAIPDTPFIGKGRWTIPNFVLGDRKFLQEIEEKGKSLLNDLRAQPDTCADSKDAQIKWKSFKEDITKTARRFAKTPLTWTERRLKEIEVRLRILNNDLVENEDTKKEEIRCLQFEESELITLQFNARRDITAARNQLEGETVCKEKIGS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias413-442Polar residues
Compositional bias450-483Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABXXO010000007
EMBL· GenBank· DDBJ
KAF7773480.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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