A0A8H6B1W0 · A0A8H6B1W0_9HELO

  • Protein
    Arginine biosynthesis bifunctional protein ArgJ, mitochondrial
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N2-acetyl-L-ornithine (cyclic): step 1/1.
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 1/4.

Features

Showing features for site, binding site, active site.

Type
IDPosition(s)Description
Site163Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Site164Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Binding site200substrate
Binding site229substrate
Site239-240Cleavage; by autolysis
Active site240Nucleophile
Binding site240substrate
Binding site334substrate
Binding site474substrate

GO annotations

AspectTerm
Cellular Componentmitochondrial matrix
Molecular Functionglutamate N-acetyltransferase activity
Molecular FunctionL-glutamate N-acetyltransferase activity
Biological Processarginine biosynthetic process
Biological Processornithine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Including 2 domains:

  • Recommended name
    Glutamate N-acetyltransferase
  • EC number
  • Short names
    GAT
  • Alternative names
    • Ornithine acetyltransferase
      (OATase
      )
    • Ornithine transacetylase
  • Recommended name
    Amino-acid acetyltransferase
  • EC number
  • Alternative names
    • N-acetylglutamate synthase
      (AGS
      )

Gene names

    • ORF names
      Bfra_001947sa

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BVB16
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Leotiomycetes > Helotiales > Sclerotiniaceae > Botrytis

Accessions

  • Primary accession
    A0A8H6B1W0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_50350239261-239Arginine biosynthesis bifunctional protein ArgJ alpha chain
ChainPRO_5035023925240-479Arginine biosynthesis bifunctional protein ArgJ beta chain

Post-translational modification

The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.

Keywords

Interaction

Subunit

Heterodimer of an alpha and a beta chain.

Family & Domains

Sequence similarities

Belongs to the ArgJ family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    479
  • Mass (Da)
    52,002
  • Last updated
    2022-01-19 v1
  • MD5 Checksum
    0E2F4D19758BFC43299AE6B1B8E606F7
MYRVSHTACFRKKPLQVNIQYRSFTKFDSFGNSPIPASKQRFVPTSGTYPKGFLIGSTNVGIKPSGLSQPDLILVTSEKQWEACGAAVLTKNEFPAPSVLVTRELIKESRGRRVRGVVANSWCANLLTGERGLEDSRKMSEEAGMVLGEGKGKGKDPVMVMHTGKLLLPIDDIIQGFPKLHQNMGTTHNHWLQAARGICTTDTFPKLLSRTFSLPSLPNTKFSLAGITKGAGMIHPNMATTLGIICTDAPITPPALQQLLSTAADKSYNCISIEGDTSTNDMVTMFANGAAAPTHSPIDFDTLAASQSEDFVAFQKILIEFMADLAKLVVRDGEGATKFITIRVRGAPTYPAGKHIASVIARSVLFKMGVYGKDPNPIGVLAALGYSLMDTKFAGKGIINCELTSVSFVPVDGAEELNFVKRGKLMEVDESRVKELMEKEDVEVVVDLRDDGGGKGEEAVYWTCDITHEFVTINGDFRN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABFCT010000003
EMBL· GenBank· DDBJ
KAF5877580.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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