A0A8H5K4G5 · A0A8H5K4G5_9HYPO

  • Protein
    Translation factor GUF1 mitochondrial
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site.

119382004006008001,0001,2001,4001,6001,800
TypeIDPosition(s)Description
Binding site1348-1355GTP (UniProtKB | ChEBI)
Binding site1413-1417GTP (UniProtKB | ChEBI)
Binding site1467-1470GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentmitochondrial matrix
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functionmitochondrial ribosome binding
Biological Processpositive regulation of translation
Biological Processtranslation

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Translation factor GUF1 mitochondrial

Gene names

    • ORF names
      FPHYL_4495

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NRRL 13617
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium fujikuroi species complex

Accessions

  • Primary accession
    A0A8H5K4G5

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region, compositional bias, coiled coil, domain.

Type
IDPosition(s)Description
Region1-158Disordered
Compositional bias26-42Polar residues
Compositional bias54-68Polar residues
Compositional bias126-158Polar residues
Compositional bias180-208Polar residues
Region180-244Disordered
Compositional bias221-244Polar residues
Region271-368Disordered
Compositional bias282-320Polar residues
Region427-571Disordered
Compositional bias483-497Polar residues
Compositional bias513-537Polar residues
Coiled coil688-715
Region756-847Disordered
Compositional bias769-803Polar residues
Compositional bias807-822Pro residues
Compositional bias823-847Polar residues
Compositional bias885-917Polar residues
Region885-989Disordered
Compositional bias935-980Polar residues
Region1202-1221Disordered
Domain1339-1520Tr-type G

Sequence similarities

Belongs to the GTP-binding elongation factor family. LepA subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,938
  • Mass (Da)
    212,904
  • Last updated
    2022-01-19 v1
  • Checksum
    DE487373F0219C2F
MHDGQISSSPHQFLNHNHNHHHHQRPSASPSSAATASATATVTVPPPWALPAYASSASVSTDSRPATGRSHYNYPHRDPSRSALSPSVSPSLNARPHHRAPGPRLPRTSSLLPPPHIEPSPRAVTFQRSDRLSPTPTPTPGGGSNGNGNSNGSPHNAAESSWLLNRLSSSTVSTNFSRVSALPPRANHTNSRLGKSPSIDATTFIDNSPPPSKPSPRKLQKNHRPSTSVSNPDTFIFRPSEDRTQLPQSLPLIVTLSPLEAPAALSDILNVKSEGAGPGSGSSEPGRSTGARQEGQSLKQSDNSDSPARSVTSTPGSARSMAAYRPNMQYDQDQEAYPPQRGHSRSRSGKGSNDRGRAKPPSQKAMLHRALQKANTAVQLDNAQNFKGAREAYAEACDLLQQVLQKTTADEDKRKLEAIRRTYTSRIDELDQMAPWQEEETKALPARPESLAQHSESESVLRLDDDDDEPNDTAVFDNATAARIDSRSPQPQIVSSPPRDDRQGYKRRSPQNKPKPIVTSLTPEPGLLQSSFSRSPVRLRTPEHFLPQRPADQYMPAPLSPRRPLSPAKEVNDMDEPVRTDFSMSNDQQNDHAQEHNVPQTHFREDSMNSWLDPIDESGGSTASSVHSRTSSLGFRRKHIRGVSGETEAEFDTALDAAIEAAYDDGYEPMSPMDHRRMVSVDAGEEVVANAMRKVELARQKVRETEQELYEMERDNRSQQQYQSYEYQGTPNDFYNDNSSDEEERILDEIARDYGLESYRHRPPPPRESDSSGVTSRTWHSSQGSNPPTGATSLSTVTELPPPLTHLTQGPAAPPPTQSLPELPQRPGSSAQSVRNRRLSGQNPKQLKIETSKLALPMQSYADANQAKSAPLSSQNVDATIEPDTKAASANHRQPSPPLFEASPTDMTGSRPTPSPFGQLGSEKGDDDITGSPNTRKLRKNFSSSSLRSMKSRNMSLTHLEEGSDLSPGTPGSNPFGSLNAPSVPALPTPLATSFRERSETNAAGLSLFDDHFYSPTSPGSPNPLISDPPAPLEPCPTDFMLRPFWLMRCLYQTLAHPRGGYISSKLFVSRDVWRVKGVKLKNIEDKVANCDFLTAALLKIARVDTYDADAVLEEMQSLEGILEQVQTALSRKLGNEVGVHGSGALFKDASTGDGDAATGVPRSASVSGKSSFSWRRLRSKNSAVGLGGSYMSRVNTETSKDIPSIASLPMTPTPTNRPPKRDLAQVQFTGPNAMYMSSLARLFDAAQAIDQIARQVEDPGLRHADKTQVGLELCTRHAAEFFGFYMSLAWSAGRAWSRRCLSQAPSFLTSRIYANLRRYATKPTPAELEARIAAIPIERYRNFCIVAHIDHGKSTLSDRLLEYTGTISASDANKQILDKLDVERERGITVKAQTCTMIHKHNGQDYLLHLVDTPGHVDFRAEVTRSYASCGGALLLVDASQGIQAQTVSNFHLAFAQDLALVPVVNKIDMPAADVPRVLQQMKDSFELDPKDAIMLSAKTGKGVPDVLPAVIERIPHPVGDEKKPLKMMLVDSWYDNFRGVVLLVRLFDGTIKAGDNVVSLGTGMKYTVGQVGIQYPHAIPQATLSAGQVGYVYFNPGMKKIQDAKLGDTFTFVGAEEKVEPYPGFEEPKPMVFVAAFPTDQSDYSRLADSIGQLVLNDRSVTLQKDHSEALGAGWRLGFLGSLHCSVFQDRLRQEHGKSVILTEPTVPSKIIWPDGSEEIVSNPALFPETSNPKVKQSQLLEPYVTTTITMPEEYLGRVIELCEANRGEQKSLEFFHTTQVILQYGIPTAQLVDDLFGKLKSVTKGYATLDYEDAGWRESNLVKLQLLVNRQPVDAICKVVHSSQVDRLGRQWVTKFKEHVDRQHFEVVIQATAGNRIVARETIKPFRKDVLAKLHAADVSRRRKLLEKQKEGRKRLRAVGNVIIDQSAFQSFMSR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias26-42Polar residues
Compositional bias54-68Polar residues
Compositional bias126-158Polar residues
Compositional bias180-208Polar residues
Compositional bias221-244Polar residues
Compositional bias282-320Polar residues
Compositional bias483-497Polar residues
Compositional bias513-537Polar residues
Compositional bias769-803Polar residues
Compositional bias807-822Pro residues
Compositional bias823-847Polar residues
Compositional bias885-917Polar residues
Compositional bias935-980Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAOAQ010000141
EMBL· GenBank· DDBJ
KAF5564901.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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