A0A8H5K4G5 · A0A8H5K4G5_9HYPO
- ProteinTranslation factor GUF1 mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1938 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
Catalytic activity
- GTP + H2O = GDP + phosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 1348-1355 | GTP (UniProtKB | ChEBI) | |||
Binding site | 1413-1417 | GTP (UniProtKB | ChEBI) | |||
Binding site | 1467-1470 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | mitochondrial matrix | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | mitochondrial ribosome binding | |
Biological Process | positive regulation of translation | |
Biological Process | translation |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium fujikuroi species complex
Accessions
- Primary accessionA0A8H5K4G5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for region, compositional bias, coiled coil, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-158 | Disordered | |||
Compositional bias | 26-42 | Polar residues | |||
Compositional bias | 54-68 | Polar residues | |||
Compositional bias | 126-158 | Polar residues | |||
Compositional bias | 180-208 | Polar residues | |||
Region | 180-244 | Disordered | |||
Compositional bias | 221-244 | Polar residues | |||
Region | 271-368 | Disordered | |||
Compositional bias | 282-320 | Polar residues | |||
Region | 427-571 | Disordered | |||
Compositional bias | 483-497 | Polar residues | |||
Compositional bias | 513-537 | Polar residues | |||
Coiled coil | 688-715 | ||||
Region | 756-847 | Disordered | |||
Compositional bias | 769-803 | Polar residues | |||
Compositional bias | 807-822 | Pro residues | |||
Compositional bias | 823-847 | Polar residues | |||
Compositional bias | 885-917 | Polar residues | |||
Region | 885-989 | Disordered | |||
Compositional bias | 935-980 | Polar residues | |||
Region | 1202-1221 | Disordered | |||
Domain | 1339-1520 | Tr-type G | |||
Sequence similarities
Belongs to the GTP-binding elongation factor family. LepA subfamily.
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,938
- Mass (Da)212,904
- Last updated2022-01-19 v1
- ChecksumDE487373F0219C2F
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 26-42 | Polar residues | |||
Compositional bias | 54-68 | Polar residues | |||
Compositional bias | 126-158 | Polar residues | |||
Compositional bias | 180-208 | Polar residues | |||
Compositional bias | 221-244 | Polar residues | |||
Compositional bias | 282-320 | Polar residues | |||
Compositional bias | 483-497 | Polar residues | |||
Compositional bias | 513-537 | Polar residues | |||
Compositional bias | 769-803 | Polar residues | |||
Compositional bias | 807-822 | Pro residues | |||
Compositional bias | 823-847 | Polar residues | |||
Compositional bias | 885-917 | Polar residues | |||
Compositional bias | 935-980 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAAOAQ010000141 EMBL· GenBank· DDBJ | KAF5564901.1 EMBL· GenBank· DDBJ | Genomic DNA |