A0A8H4XDZ4 · A0A8H4XDZ4_9HYPO

  • Protein
    NAD(P)H-hydrate epimerase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: Binds 1 potassium ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site61-65(6S)-NADPHX (UniProtKB | ChEBI)
Binding site62K+ (UniProtKB | ChEBI)
Binding site123K+ (UniProtKB | ChEBI)
Binding site127-133(6S)-NADPHX (UniProtKB | ChEBI)
Binding site156(6S)-NADPHX (UniProtKB | ChEBI)
Binding site159K+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionmetal ion binding
Molecular FunctionNADHX epimerase activity
Molecular Functionnucleotide binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD(P)H-hydrate epimerase
  • EC number
  • Alternative names
    • NAD(P)HX epimerase

Gene names

    • ORF names
      FSARC_1590

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NRRL 20472
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium lateritium species complex

Accessions

  • Primary accession
    A0A8H4XDZ4

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain11-217YjeF N-terminal

Sequence similarities

Belongs to the NnrE/AIBP family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    236
  • Mass (Da)
    25,459
  • Last updated
    2022-01-19 v1
  • Checksum
    81A6339C93D8D30F
MAIKTLGAKAAAALDQELMSTGAFSLDQLMELAGLAVSQAVYRLQPLDSGRRILVACGPGNNGGDGLVAARHLRQYGYSPTVFYPKRSKNDLYQRLAKQLEDLEVPFVDDFSSALSSTDHIVDAIFGFSFSGEVREPFPAVIQALQDTKLPVTSVDAPSSWDIEDGPPTSGLGSSFMPTALISLTAPKPLVKHFKGRHFIGGRFVTPAIAKKFDFEVPEYKGIDQVVEVEVAGQKL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABEXW010000085
EMBL· GenBank· DDBJ
KAF4971643.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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