A0A8H4WUF5 · A0A8H4WUF5_9HYPO

  • Protein
    ATP-dependent DNA helicase CHL1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G2/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular FunctionDNA binding
Molecular FunctionDNA helicase activity
Molecular Functionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Molecular Functioniron-sulfur cluster binding
Molecular Functionisomerase activity
Molecular Functionmetal ion binding
Biological ProcessDNA damage response
Biological Processestablishment of sister chromatid cohesion
Biological Processnucleobase-containing compound metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase CHL1
  • EC number
  • Alternative names
    • ATP-dependent DNA helicase chl1
    • Chromosome loss protein 1
    • DNA 5'-3' helicase CHL1

Gene names

    • ORF names
      FGADI_8294

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NRRL 45417
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium nisikadoi species complex

Accessions

  • Primary accession
    A0A8H4WUF5

Proteomes

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain14-442Helicase ATP-binding

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    864
  • Mass (Da)
    96,096
  • Last updated
    2022-01-19 v1
  • Checksum
    CCFF622CC9906019
MAQSEVEKVTQDLEKLDFHHPYTPYDVQEQFMKAVYDVLETGNGQVGILESPTGTGKSLSLICASLTWLRNHKSNQFEASIQESAEAYKDEPSWLVEQLLRRKREELVTRWEDREKRLETLRLKEKAQEERARKRRRVDDYVPSRSRVEDEDAEWLLDDSDDRDAGSQDALSGLSKETREILASIGLGGPKKPEEEDDLLEEEIKIYYTSRTHSQLSQFITELRRPSFPPSLPTSLAKSEETKTEAVKLLPLSSRQRLCINPTVSRLGSVQAINDRCSELQQPKSGQKCPFVPKEDLLSQTHQFRDSALATLPDIEDLHQLGKSLSVCPYYASRTALPGAEIITLPYPLLLQKSARDALGVKLEGSVVIIDEAHNIMDAVANVHAAEIKLSDLRRGRAMLGIYVKKFGKKLKGVNRVNVGRVGRVIDGLSEWMDGALKFKQEHGIVDPNDLTRPKGIDQINMFELIQYIQESKLAFKIESYISHVESEDANSKTSRSSSPVLHTLVSFLIAFTNLSSEGRIFYQKIKGPTPDIQLSYLLLSPTYAFSSIASSARAVVLAGGTMSPFDDYKDHLFPSLEPGKITTLSCGHVIPPENLCVWTLASSRPGAPPFEFSFQKRGDTEMITQLGLAILNLCSLVPDGVVIFFPSYGYLDEVVAVWQKSQGNAQPIWDRLAARKALFKESRGASSDEVLQEYSDAILGEKSKGKGALLLSVVGGKMSEGINFSDRLGRCVIVIGLPYPNIASPDWKAKIEYIETTTQNNLTAQGVAKEEAISKGKQTARDFYENACMRAVNQSIGRAIRHRGDFAAIVLVDRRYGTERIRGKLPGWIRGGLVKDSHEKGLGGLMGAVGGFFRGKKSKSQGQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABFAI010000215
EMBL· GenBank· DDBJ
KAF4950311.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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