Essential maintenance is planned to begin on Tue Jan 28 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ during this time.

A0A8H4T4Y7 · A0A8H4T4Y7_9HYPO

  • Protein
    GMP synthase (glutamine-hydrolyzing)
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    3/5

Function

function

Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site59Nucleophile
Active site151
Active site153
Binding site206-212ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionGMP synthase activity
Biological Processglutamine metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    GMP synthase (glutamine-hydrolyzing)
  • EC number
  • Alternative names
    • GMP synthetase
    • Glutamine amidotransferase

Gene names

    • ORF names
      FGADI_7487

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NRRL 45417
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium nisikadoi species complex

Accessions

  • Primary accession
    A0A8H4T4Y7

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain178-370GMPS ATP-PPase

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    514
  • Mass (Da)
    56,561
  • Last updated
    2022-01-19 v1
  • MD5 Checksum
    E8BB66A5563CA114AF421B82E209DC88
MSETLDAAPPHATFDKLKDLSWKPVGIILSGGPSSVYSADAPNVDPLVFELGVPVLGVCYGCQLIAWRVNSNNVAPGVAREYGETSMAIRKIGNHADRLFEGLGDSLNVVMSHFDKLVHLPDGFKTIATTKNSEFAGIAHDSQPVFGIQFHPEISHTERGTDIIANFALKICGARADWKMDNFSEREIVRIRKLVGDKAQVIGAVSGGVDSTVAAKLLTEAIGDRFKSILVDTGLMRLNECEQVKETLDKHLGINLTVVDGSDLFFSRLAGVTEPEAKRKIIGETYKVIDLFEIEALRIEKEAENTPFAGKVEWFLQGTLYAHHNAGGLPARMQNGEAHLKLLEPLRELFKDEVRAFGRQLQIHEELIGRHPFPGPGLGIRIIGEVTRERVEIVRKADHIFISMIREAGIYDEVTQAYAALDTNRAVGVQGDARAYGYICVLRAVTSLDMMSAEPYEFEWSLLKAISRRIVNEVDGIARVVYDTTSKPPGESLLYASPSHACDIDRPTGTIELE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABFAI010000178
EMBL· GenBank· DDBJ
KAF4951416.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help