A0A8H4T4Y7 · A0A8H4T4Y7_9HYPO
- ProteinGMP synthase (glutamine-hydrolyzing)
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids514 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.
Catalytic activity
- XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H+
Pathway
Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 59 | Nucleophile | |||
Active site | 151 | ||||
Active site | 153 | ||||
Binding site | 206-212 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | GMP synthase activity | |
Biological Process | glutamine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGMP synthase (glutamine-hydrolyzing)
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium nisikadoi species complex
Accessions
- Primary accessionA0A8H4T4Y7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length514
- Mass (Da)56,561
- Last updated2022-01-19 v1
- MD5 ChecksumE8BB66A5563CA114AF421B82E209DC88
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JABFAI010000178 EMBL· GenBank· DDBJ | KAF4951416.1 EMBL· GenBank· DDBJ | Genomic DNA |