A0A8H4PUP6 · A0A8H4PUP6_9HYPO

  • Protein
    Deoxyuridine 5'-triphosphate nucleotidohydrolase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.

GO annotations

AspectTerm
Molecular FunctiondUTP diphosphatase activity
Molecular Functionmagnesium ion binding
Biological ProcessdUMP biosynthetic process
Biological ProcessdUTP catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Deoxyuridine 5'-triphosphate nucleotidohydrolase
  • EC number
  • Short names
    dUTPase
  • Alternative names
    • dUTP pyrophosphatase

Gene names

    • ORF names
      G6O67_002633

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • IOZ07
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Ophiocordycipitaceae > Ophiocordyceps

Accessions

  • Primary accession
    A0A8H4PUP6

Proteomes

Interaction

Subunit

Homotrimer.

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-26Polar residues
Region1-27Disordered
Domain38-166dUTPase-like

Sequence similarities

Belongs to the dUTPase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    168
  • Mass (Da)
    17,740
  • Last updated
    2022-01-19 v1
  • Checksum
    54EA15DD25BD2BEB
MSAADPSSPPNKRIKTTDQGSSNMEPAPALQVRKLSDKGRLPTRGSAFAAGYDLYAAKDTTVPARGKVLVDTDISIAVPAGTYGRIAPRSGLASKHFIDTGAGVIDADYRGQVKVLLFNHADADFDIKEGDRVAQLVLERIVTPDVVEVQELEESVRGAGGFGSTGKQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-26Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAVMX010000003
EMBL· GenBank· DDBJ
KAF4510765.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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