A0A8H4PB63 · A0A8H4PB63_9HYPO
- ProteinGlutathione hydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids566 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 101 | L-glutamate (UniProtKB | ChEBI) | |||
Active site | 375 | Nucleophile | |||
Binding site | 393-395 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 417 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 445-446 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 468 | L-glutamate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | acyltransferase activity | |
Molecular Function | glutathione hydrolase activity | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium decemcellulare species complex
Accessions
- Primary accessionA0A8H4PB63
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-19 | ||||
Chain | PRO_5034053561 | 20-566 | Glutathione hydrolase | ||
Structure
Sequence
- Sequence statusComplete
- Length566
- Mass (Da)61,522
- Last updated2022-01-19 v1
- MD5 Checksum765ECD549E11E5CEA3FB580C72641D49
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAADYS010000936 EMBL· GenBank· DDBJ | KAF4466050.1 EMBL· GenBank· DDBJ | Genomic DNA |